Multiple choice

The majority of ovarian epithelial cancers occurring on a hereditary basis originates in a woman with germline mutations in which of the following genes?

  1. pRb

  2. MSH2

  3. p53

  4. BRCA 1

  5. BRCA 2
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Mutations in the BRCA 1 gene (located on chromosome 17) cause most of the ovarian epithelial cancers seen on a hereditary basis.

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