Multiple choice

Which of the following is most pertinent to common variable immune deficiency disorders?

  1. They are always present before the age of 10 years.

  2. They are caused due to a single gene defect on the X chromosome.

  3. They affect 1 in 500 of the population.

  4. Patients are treated by replacement immunoglobulin, intravenously or subcutaneously.

  5. Most patients die from complications of malignancy.
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Replacement immunoglobulin therapy is also used in CD40 ligand deficiency. Ig is prepared from the plasma collected from a large number of normal individuals, usually between 10,000-50,000, who have been carefully screened to make sure they are healthy and do not harbor certain infectious diseases. The plasma contains a broad range of specific antibodies to many different types of bacteria and viruses.

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