Chemistry ยท Biology
Pharmacology and Therapeutics
1,643 Questions
Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.
Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests
Pharmacology and Therapeutics Questions
What is the mechanism of action of leflunomide?
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Inhibits dihydroorotate dehydrogenase
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Inhibits purine synthesis
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Inhibits DNA synthesis
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All of the above
A
Correct answer
Explanation
Leflunomide inhibits dihydroorotate dehydrogenase, an enzyme that is essential for pyrimidine synthesis.
What is the mechanism of action of mycophenolate mofetil?
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Inhibits inosine monophosphate dehydrogenase
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Inhibits purine synthesis
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Inhibits DNA synthesis
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All of the above
A
Correct answer
Explanation
Mycophenolate mofetil inhibits inosine monophosphate dehydrogenase, an enzyme that is essential for guanine synthesis.
Which of the following is a side effect of mycophenolate mofetil?
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Myelosuppression
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Gastrointestinal upset
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Hepatotoxicity
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All of the above
D
Correct answer
Explanation
Mycophenolate mofetil can cause myelosuppression, gastrointestinal upset, and hepatotoxicity.
What are the medications used to treat angina?
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Nitroglycerin
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Beta-blockers
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Calcium channel blockers
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Statins
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Aspirin
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All of the above
F
Correct answer
Explanation
The medications used to treat angina include nitroglycerin, beta-blockers, calcium channel blockers, statins, and aspirin.
What is the surgery used to treat angina?
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Coronary artery bypass grafting (CABG)
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Percutaneous coronary intervention (PCI)
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Both of the above
C
Correct answer
Explanation
The surgery used to treat angina is coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI).
Which of the following medications can cause tearing as a side effect?
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Antidepressants
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Antihistamines
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Decongestants
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All of the above
D
Correct answer
Explanation
Antidepressants, antihistamines, and decongestants can all cause tearing as a side effect. This is because these medications can affect the production or drainage of tears.
What is the recommended treatment for tearing caused by allergies?
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Antihistamines
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Decongestants
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Nasal irrigation
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All of the above
D
Correct answer
Explanation
The recommended treatment for tearing caused by allergies typically involves a combination of antihistamines, decongestants, and nasal irrigation. These treatments help to reduce inflammation, relieve nasal congestion, and clear allergens from the nasal passages.
What is the most commonly used illicit drug in India?
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Cannabis
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Opium
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Heroin
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Cocaine
A
Correct answer
Explanation
Cannabis is the most commonly used illicit drug in India, with an estimated 2.8% of adults reporting cannabis use in the past year.
What is the most common mode of substance administration in India?
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Oral
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Inhalation
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Injection
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Transdermal
A
Correct answer
Explanation
Oral administration is the most common mode of substance administration in India, accounting for approximately 80% of all substance use.
What is the primary psychoactive compound found in coffee?
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Caffeine
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Theobromine
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Theophylline
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Chlorogenic acid
A
Correct answer
Explanation
Caffeine is a central nervous system stimulant that is found in coffee, tea, and other plants. It is the primary psychoactive compound in coffee and is responsible for its energizing effects.
What is the primary active compound found in turmeric, responsible for its anti-inflammatory and antioxidant properties?
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Curcumin
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Gingerol
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Quercetin
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Resveratrol
A
Correct answer
Explanation
Curcumin is the main bioactive compound in turmeric, known for its potent anti-inflammatory and antioxidant effects.
Which of the following medications is commonly used to prevent acute nausea and vomiting?
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Ondansetron
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Metoclopramide
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Prochlorperazine
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Granisetron
A
Correct answer
Explanation
Ondansetron is a commonly used medication for preventing acute nausea and vomiting. Metoclopramide, prochlorperazine, and granisetron are also used for this purpose.
What is the most common type of constipation experienced by cancer patients?
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Opioid-induced constipation
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Mechanical constipation
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Functional constipation
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Idiopathic constipation
A
Correct answer
Explanation
Opioid-induced constipation is the most common type of constipation experienced by cancer patients. It is caused by the use of opioid pain medications.
Which of the following medications is commonly used to treat opioid-induced constipation?
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Lactulose
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Polyethylene glycol
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Bisacodyl
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Senna
A
Correct answer
Explanation
Lactulose is a commonly used medication for treating opioid-induced constipation. Polyethylene glycol, bisacodyl, and senna are also used for this purpose.
Which of the following medications is commonly used to prevent breakthrough nausea and vomiting?
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Ondansetron
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Metoclopramide
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Prochlorperazine
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Granisetron
A
Correct answer
Explanation
Ondansetron is a commonly used medication for preventing breakthrough nausea and vomiting. Metoclopramide, prochlorperazine, and granisetron are also used for this purpose.