Chemistry ยท Biology

Pharmacology and Therapeutics

1,643 Questions

Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.

Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests

Pharmacology and Therapeutics Questions

Multiple choice

Which of the following drugs can interfere with the absorption of iron?

  1. Tetracycline

  2. Ciprofloxacin

  3. Calcium supplements

  4. All of the above
Reveal answer Fill a bubble to check yourself
Correct answer
Explanation

Tetracycline, ciprofloxacin, and calcium supplements can all interfere with the absorption of iron. Tetracycline and ciprofloxacin can chelate iron and prevent its absorption in the small intestine, while calcium supplements can bind to iron and form insoluble complexes that are not absorbed.

Multiple choice

Which of the following drugs can increase the excretion of calcium?

  1. Loop diuretics

  2. Thiazide diuretics

  3. ACE inhibitors

  4. Beta-blockers
Reveal answer Fill a bubble to check yourself
Correct answer
Explanation

Loop diuretics can increase the excretion of calcium by inhibiting the reabsorption of calcium in the kidneys.

Multiple choice

Which of the following drugs can interfere with the absorption of folate?

  1. Methotrexate

  2. Sulfasalazine

  3. Trimethoprim

  4. All of the above
Reveal answer Fill a bubble to check yourself
Correct answer
Explanation

Methotrexate, sulfasalazine, and trimethoprim can all interfere with the absorption of folate. Methotrexate and sulfasalazine can inhibit the transport of folate across the intestinal mucosa, while trimethoprim can interfere with the metabolism of folate.

Multiple choice

Which of the following drugs can increase the excretion of magnesium?

  1. Loop diuretics

  2. Thiazide diuretics

  3. ACE inhibitors

  4. Beta-blockers
Reveal answer Fill a bubble to check yourself
Correct answer
Explanation

Loop diuretics can increase the excretion of magnesium by inhibiting the reabsorption of magnesium in the kidneys.

Multiple choice

Which of the following nutrients can interfere with the metabolism of cyclosporine?

  1. Grapefruit juice

  2. St. John's wort

  3. Garlic

  4. All of the above
Reveal answer Fill a bubble to check yourself
Correct answer
Explanation

Grapefruit juice, St. John's wort, and garlic can all interfere with the metabolism of cyclosporine. Grapefruit juice and St. John's wort can increase the metabolism of cyclosporine, while garlic can decrease the metabolism of cyclosporine.

Multiple choice

Which of the following drugs can increase the excretion of zinc?

  1. Penicillamine

  2. Furosemide

  3. Hydrochlorothiazide

  4. All of the above
Reveal answer Fill a bubble to check yourself
Correct answer
Explanation

Penicillamine, furosemide, and hydrochlorothiazide can all increase the excretion of zinc. Penicillamine can chelate zinc and increase its excretion in the urine, while furosemide and hydrochlorothiazide can increase the excretion of zinc in the urine by inhibiting its reabsorption in the kidneys.

Multiple choice

What is the most common type of antiparasitic drug used to treat infectious diseases?

  1. Mebendazole

  2. Albendazole

  3. Praziquantel

  4. Ivermectin
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Mebendazole is the most common type of antiparasitic drug used to treat infectious diseases, as it is effective against a wide range of parasites.

Multiple choice

What is the recommended treatment for HIV-associated rheumatoid arthritis?

  1. Nonsteroidal anti-inflammatory drugs (NSAIDs)

  2. Disease-modifying antirheumatic drugs (DMARDs)

  3. Glucocorticoids

  4. All of the above
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Treatment for HIV-associated rheumatoid arthritis typically involves a combination of nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs), and glucocorticoids.

Multiple choice

What are the medications that can be used to treat atherosclerosis?

  1. Statins

  2. Blood pressure medications

  3. Antiplatelet medications

  4. Anticoagulants

  5. All of the above
Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

The medications that can be used to treat atherosclerosis include statins, blood pressure medications, antiplatelet medications, and anticoagulants.

Multiple choice

Which of the following medications is commonly used to treat acne in adolescents?

  1. Isotretinoin

  2. Benzoyl peroxide

  3. Salicylic acid

  4. Clindamycin
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Isotretinoin is a retinoid medication that is effective in treating severe acne in adolescents.

Multiple choice

Which of the following is an example of a targeted therapy for cancer?

  1. Cisplatin

  2. Tamoxifen

  3. Trastuzumab

  4. Doxorubicin
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Trastuzumab is a targeted therapy that targets the HER2 protein, which is overexpressed in some types of breast cancer.

Multiple choice

Which of the following is an example of a checkpoint inhibitor used in immunotherapy?

  1. Pembrolizumab

  2. Imatinib

  3. Rituximab

  4. Bevacizumab
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Pembrolizumab is a checkpoint inhibitor that targets the PD-1 protein, which is expressed on T cells and helps regulate the immune response.

Multiple choice

Which of the following is an example of a CAR T-cell therapy?

  1. Avastin

  2. Herceptin

  3. Keytruda

  4. Yescarta
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Yescarta is a CAR T-cell therapy that targets the CD19 protein, which is expressed on B cells.

Multiple choice

Which of the following is an example of a targeted therapy for lung cancer?

  1. Erlotinib

  2. Doxorubicin

  3. Cisplatin

  4. Tamoxifen
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Erlotinib is a targeted therapy that targets the EGFR protein, which is overexpressed in some types of lung cancer.

Multiple choice

Which of the following is NOT a route of administration for psychopharmacological agents?

  1. Oral

  2. Intravenous

  3. Intramuscular

  4. Transdermal
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Transdermal is not a common route of administration for psychopharmacological agents.