Chemistry ยท Biology
Pharmacology and Therapeutics
1,699 Questions
Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.
Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests
Pharmacology and Therapeutics Questions
What is the most common side effect of isotretinoin?
-
Dry skin
-
Headache
-
Nausea
-
Increased sun sensitivity
A
Correct answer
Explanation
Dry skin is the most common side effect of isotretinoin, which can be managed with moisturizers.
What is the most common side effect of methylphenidate?
-
Insomnia
-
Loss of appetite
-
Headache
-
Increased heart rate
A
Correct answer
Explanation
Insomnia is the most common side effect of methylphenidate, which can be managed with sleep hygiene techniques.
What is the most common side effect of atypical antipsychotics?
-
Weight gain
-
Increased appetite
-
Sedation
-
Extrapyramidal symptoms
A
Correct answer
Explanation
Weight gain is the most common side effect of atypical antipsychotics, which can be managed with diet and exercise.
What is the most common side effect of SSRIs in the treatment of OCD?
-
Nausea
-
Headache
-
Diarrhea
-
Sexual dysfunction
A
Correct answer
Explanation
Nausea is the most common side effect of SSRIs in the treatment of OCD, which typically resolves within a few weeks.
What is the most common side effect of SSRIs in the treatment of PTSD?
-
Nausea
-
Headache
-
Diarrhea
-
Sexual dysfunction
A
Correct answer
Explanation
Nausea is the most common side effect of SSRIs in the treatment of PTSD, which typically resolves within a few weeks.
Which of the following is an example of a targeted therapy for cancer?
-
Cisplatin
-
Tamoxifen
-
Trastuzumab
-
Doxorubicin
C
Correct answer
Explanation
Trastuzumab is a targeted therapy that targets the HER2 protein, which is overexpressed in some types of breast cancer.
Which of the following is an example of a checkpoint inhibitor used in immunotherapy?
-
Pembrolizumab
-
Imatinib
-
Rituximab
-
Bevacizumab
A
Correct answer
Explanation
Pembrolizumab is a checkpoint inhibitor that targets the PD-1 protein, which is expressed on T cells and helps regulate the immune response.
Which of the following is an example of a CAR T-cell therapy?
-
Avastin
-
Herceptin
-
Keytruda
-
Yescarta
D
Correct answer
Explanation
Yescarta is a CAR T-cell therapy that targets the CD19 protein, which is expressed on B cells.
Which of the following is an example of a targeted therapy for lung cancer?
-
Erlotinib
-
Doxorubicin
-
Cisplatin
-
Tamoxifen
A
Correct answer
Explanation
Erlotinib is a targeted therapy that targets the EGFR protein, which is overexpressed in some types of lung cancer.
Which of the following is NOT a route of administration for psychopharmacological agents?
-
Oral
-
Intravenous
-
Intramuscular
-
Transdermal
D
Correct answer
Explanation
Transdermal is not a common route of administration for psychopharmacological agents.
The process by which a drug is absorbed into the bloodstream is known as:
-
Distribution
-
Metabolism
-
Excretion
-
Absorption
D
Correct answer
Explanation
Absorption is the process by which a drug is taken up into the body from its site of administration.
The distribution of a drug throughout the body is influenced by its:
-
Protein binding
-
Lipid solubility
-
Molecular weight
-
All of the above
D
Correct answer
Explanation
All of the above factors influence the distribution of a drug throughout the body.
The process by which a drug is broken down into smaller molecules is known as:
-
Metabolism
-
Excretion
-
Distribution
-
Absorption
A
Correct answer
Explanation
Metabolism is the process by which a drug is broken down into smaller molecules.
The primary site of metabolism for most psychopharmacological agents is the:
-
Liver
-
Kidneys
-
Lungs
-
Brain
A
Correct answer
Explanation
The liver is the primary site of metabolism for most psychopharmacological agents.
The process by which a drug is eliminated from the body is known as:
-
Metabolism
-
Excretion
-
Distribution
-
Absorption
B
Correct answer
Explanation
Excretion is the process by which a drug is eliminated from the body.