Chemistry ยท Biology
Pharmacology and Therapeutics
1,643 Questions
Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.
Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests
Pharmacology and Therapeutics Questions
How does substance abuse affect wound healing?
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It speeds up wound healing.
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It slows down wound healing.
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It has no effect on wound healing.
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It increases wound healing.
B
Correct answer
Explanation
Substance abuse can slow down wound healing, which can increase the risk of infection.
Which of the following is not a benzodiazepine?
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Diazepam
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Lorazepam
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Alprazolam
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Buspirone
D
Correct answer
Explanation
Buspirone is not a benzodiazepine, but rather an anxiolytic of a different class.
Which of the following is not a stimulant?
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Amphetamine
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Methylphenidate
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Caffeine
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Clonidine
D
Correct answer
Explanation
Clonidine is not a stimulant, but rather an antihypertensive.
Which of the following is not an opioid?
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Morphine
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Heroin
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Fentanyl
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Buprenorphine
D
Correct answer
Explanation
Buprenorphine is not an opioid, but rather an opioid antagonist.
Which of the following is not an anticonvulsant?
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Phenytoin
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Carbamazepine
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Valproate
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Lithium
D
Correct answer
Explanation
Lithium is not an anticonvulsant, but rather a mood stabilizer.
Which of the following is not a muscle relaxant?
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Baclofen
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Diazepam
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Cyclobenzaprine
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Methocarbamol
B
Correct answer
Explanation
Diazepam is not a muscle relaxant, but rather an anxiolytic.
What is the primary psychoactive component of marijuana?
A
Correct answer
Explanation
Tetrahydrocannabinol (THC) is the primary psychoactive compound in marijuana, responsible for its intoxicating effects.
What is the mechanism of action of rivastigmine?
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Inhibits acetylcholinesterase
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Inhibits butyrylcholinesterase
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Increases the release of acetylcholine
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Increases the reuptake of acetylcholine
A
Correct answer
Explanation
Rivastigmine inhibits acetylcholinesterase, thereby increasing the levels of acetylcholine in the brain.
What is the mechanism of action of memantine?
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Inhibits acetylcholinesterase
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Inhibits butyrylcholinesterase
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Blocks NMDA receptors
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Increases the release of acetylcholine
C
Correct answer
Explanation
Memantine blocks NMDA receptors, thereby reducing excitotoxicity and neuronal damage.
Which of the following is an immunosuppressive drug used to prevent rejection in organ transplantation?
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Cyclosporine
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Tacrolimus
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Azathioprine
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All of the above
D
Correct answer
Explanation
Cyclosporine, tacrolimus, and azathioprine are all immunosuppressive drugs used to prevent rejection in organ transplantation.
What is the mechanism of action of cyclosporine?
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Inhibits calcineurin
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Inhibits T cell activation
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Inhibits B cell activation
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All of the above
A
Correct answer
Explanation
Cyclosporine inhibits calcineurin, a phosphatase that is essential for T cell activation.
What is the mechanism of action of tacrolimus?
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Inhibits calcineurin
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Inhibits T cell activation
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Inhibits B cell activation
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All of the above
A
Correct answer
Explanation
Tacrolimus inhibits calcineurin, a phosphatase that is essential for T cell activation.
What is the mechanism of action of azathioprine?
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Inhibits purine synthesis
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Inhibits DNA synthesis
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Inhibits RNA synthesis
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All of the above
A
Correct answer
Explanation
Azathioprine inhibits purine synthesis, which is essential for DNA and RNA synthesis.
Which of the following is an immunosuppressive drug used to treat autoimmune diseases?
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Methotrexate
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Leflunomide
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Mycophenolate mofetil
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All of the above
D
Correct answer
Explanation
Methotrexate, leflunomide, and mycophenolate mofetil are all immunosuppressive drugs used to treat autoimmune diseases.
What is the mechanism of action of methotrexate?
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Inhibits dihydrofolate reductase
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Inhibits purine synthesis
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Inhibits DNA synthesis
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All of the above
A
Correct answer
Explanation
Methotrexate inhibits dihydrofolate reductase, an enzyme that is essential for DNA synthesis.