Chemistry ยท Biology
Pharmacology and Therapeutics
1,643 Questions
Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.
Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests
Pharmacology and Therapeutics Questions
Which of the following is NOT a type of drug target?
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Receptors
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Enzymes
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Ion Channels
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Nucleic Acids
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Proteins
E
Correct answer
Explanation
Proteins are not a type of drug target.
Which of the following is NOT a type of drug formulation?
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Tablets
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Capsules
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Injections
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Ointments
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Suppositories
E
Correct answer
Explanation
Suppositories are not a type of drug formulation.
What is the first-line treatment for malaria?
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Artemisinin-based combination therapy (ACT)
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Chloroquine
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Sulfadoxine-pyrimethamine (SP)
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Mefloquine
A
Correct answer
Explanation
Artemisinin-based combination therapy (ACT) is the first-line treatment for malaria.
What is the recommended treatment for severe malaria?
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Intravenous artesunate
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Intravenous quinine
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Intravenous mefloquine
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Intravenous doxycycline
A
Correct answer
Explanation
Intravenous artesunate is the recommended treatment for severe malaria.
Which of the following is an example of a patient safety risk in medication administration?
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Incorrect dosage
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Omission of a prescribed medication
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Administration of a medication to the wrong patient
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All of the above
D
Correct answer
Explanation
Incorrect dosage, omission of a prescribed medication, and administration of a medication to the wrong patient are all examples of patient safety risks associated with medication administration.
What is the primary treatment for asthma?
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Bronchodilators
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Steroids
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Antibiotics
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Surgery
A
Correct answer
Explanation
Bronchodilators are the primary treatment for asthma. They work by relaxing the muscles around the airways, which helps to open up the airways and improve airflow.
Which of the following is an example of a biopharmaceutical?
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Aspirin
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Insulin
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Ibuprofen
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Acetaminophen
B
Correct answer
Explanation
Insulin is a biopharmaceutical because it is produced using recombinant DNA technology, which involves the insertion of a gene encoding human insulin into a host organism, such as bacteria or yeast.
Which of the following is an example of a monoclonal antibody biopharmaceutical?
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Rituximab
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Trastuzumab
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Bevacizumab
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All of the above
D
Correct answer
Explanation
Rituximab, trastuzumab, and bevacizumab are all examples of monoclonal antibody biopharmaceuticals. These drugs are produced using hybridoma technology, which involves the fusion of a B cell with a myeloma cell to create a hybridoma cell that can produce monoclonal antibodies.
Which of the following is a common type of pharmaceutical derived from petrochemicals?
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Aspirin
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Ibuprofen
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Paracetamol
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All of the above
D
Correct answer
Explanation
Aspirin, ibuprofen, and paracetamol are all common types of pharmaceuticals derived from petrochemicals. They are used to relieve pain, fever, and inflammation.
What is the primary mechanism of action of antihistamines in allergy treatment?
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Inhibiting the release of inflammatory mediators
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Blocking the binding of IgE to mast cells
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Reducing the production of Th2 cytokines
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Preventing the activation of eosinophils
B
Correct answer
Explanation
Antihistamines work by blocking the binding of IgE to mast cells, preventing the release of inflammatory mediators.
What is the primary mechanism of action of leukotriene modifiers in asthma treatment?
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Inhibiting the release of inflammatory mediators
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Blocking the binding of IgE to mast cells
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Reducing the production of Th2 cytokines
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Preventing the activation of eosinophils
A
Correct answer
Explanation
Leukotriene modifiers work by inhibiting the release of inflammatory mediators, such as leukotrienes, from activated cells.
What is the primary mechanism of action of cromolyn sodium in asthma treatment?
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Inhibiting the release of inflammatory mediators
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Blocking the binding of IgE to mast cells
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Reducing the production of Th2 cytokines
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Preventing the activation of eosinophils
Correct answer
Explanation
Cromolyn sodium works by preventing the binding of IgE to mast cells, stabilizing mast cells, and inhibiting the release of inflammatory mediators.
Which of the following is a common dosage form in pharmaceutical manufacturing?
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Tablets
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Capsules
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Injections
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All of the above
D
Correct answer
Explanation
Tablets, capsules, and injections are all common dosage forms used to deliver pharmaceutical drugs to patients in a convenient and effective manner.
Which of the following is a common type of pharmaceutical packaging?
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Blister packs
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Bottles
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Vials
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All of the above
D
Correct answer
Explanation
Blister packs, bottles, and vials are all common types of pharmaceutical packaging used to protect and dispense drug products.
What is the primary mechanism of action of non-steroidal anti-inflammatory drugs (NSAIDs)?
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Inhibiting cyclooxygenase enzymes
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Blocking dopamine receptors
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Increasing GABA levels
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Stimulating glutamate receptors
A
Correct answer
Explanation
NSAIDs, such as ibuprofen and naproxen, work primarily by inhibiting cyclooxygenase enzymes, reducing the production of prostaglandins, which are involved in pain, inflammation, and fever.