Chemistry · Biology
Pharmacology and Therapeutics
1,643 Questions
Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.
Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests
Pharmacology and Therapeutics Questions
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cytochrome
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alpha 1-antitrypsin
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NADH dehydrogenase
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monoamine oxidase
A
Correct answer
Explanation
Cyanide inhibits cytochrome c oxidase (Complex IV) in the mitochondrial electron transport chain, blocking cellular respiration. This prevents ATP production and leads to cellular asphyxiation. Alpha 1-antitrypsin is a protease inhibitor, NADH dehydrogenase is Complex I, and monoamine oxidase breaks down neurotransmitters.
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bolus
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injection
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insufflation
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sublingual
D
Correct answer
Explanation
Sublingual refers to the pharmacological route of administration by which drugs diffuse into the blood through tissues under the tongue. Many pharmaceuticals are designed for sublingual administration, including cardiovascular drugs, steroids, barbiturates, enzymes, and increasingly, vitamins.
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antihistamine
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antipsychotic
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beta blockers
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dissociatives
C
Correct answer
Explanation
Beta blockers are a class of drugs used for various indications, but particularly for the management of cardiac arrhythmias, cardioprotection after myocardial infarction (heart attack), and hypertension.
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Carisoprodol
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Zaleplon
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Zolpidem
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Zopiclone
A
Correct answer
Explanation
Carisoprodol is a centrally-acting skeletal muscle relaxant. Carisoprodol is slightly soluble in water and freely soluble in alcohol, chloroform and acetone.
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Propranolol
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Atenolol
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Chlorpromazine
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Doxylamine
C
Correct answer
Explanation
Chlorpromazine is a typical antipsychotic. It works on a variety of receptors in the central nervous system, producing anticholinergic, antidopaminergic, antihistaminic, and weak antiadrenergic effects.
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Intramuscular
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Intravenous
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Intraperitoneal
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Intraosseous
B
Correct answer
Explanation
Intravenous therapy or IV therapy is the giving of substances directly into a vein. Therapies administered intravenously are often called specialty pharmaceuticals. It is commonly referred to as a drip because many systems of administration employ a drip chamber, which prevents air entering the blood stream (air embolism) and allows an estimate of flow rate.
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Atropine
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Diphenhydramine hydrochloride
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Hyoscyamine
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Scopolamine
B
Correct answer
Explanation
Diphenhydramine hydrochloride is a first-generation antihistamine mainly used to treat allergies.It has a powerful hypnotic effect, and for this reason is often used as a nonprescription sleep aid and a mild anxiolytic.
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emtricitabine
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cidofovir
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lamivudine
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darunavir
B
Correct answer
Explanation
Cidofovir is an injectable antiviral medicine for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. It suppresses CMV replication by selective inhibition of viral DNA polymerase and, therefore, prevents viral replication and transcription.
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Abacavir (ABC)
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Aciclovir
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Adefovir dipivoxil
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Amantadine
B
Correct answer
Explanation
Aciclovir is a guanosine analogue antiviral drug. One of the most commonly-used antiviral drugs, it is primarily used for the treatment of herpes simplex virus infections, as well as in the treatment of varicella zoster (chickenpox) and herpes zoster (shingles).
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Amprenavir
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Ampligen
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Arbidol
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Atazanavir
C
Correct answer
Explanation
Arbidol is an antiviral treatment for influenza infection .
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Edoxudine
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Efavirenz
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Emtricitabine
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None of these
D
Correct answer
Explanation
All drugs given above are antiviral drugs.
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Fomivirsen
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Foscarnet
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Ganciclovir
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Inosine pranobex
D
Correct answer
Explanation
Inosine pranobex is a combinatinon of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug. Inosine pranobex has no effect on viral cells itself. It acts as a powerful immunostimulant.
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Chromium dioxide
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Chromium trioxide
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Chromyl chloride
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Cisplatin
D
Correct answer
Explanation
Cisplatin, is a chemotherapy drug. It is used to treat various types of cancers, including sarcomas, some carcinomas (e.g., small cell lung cancer, and ovarian cancer), lymphomas, and germ cell tumors.
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farnesol
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ferrocene
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fipronil
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flunixin
D
Correct answer
Explanation
Flunixin is a non-steroidal anti-inflammatory drug (NSAID), analgesic, and antipyretic used in horses. It is often formulated as the meglumine salt.
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Fischer and Mering
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Marcellin Berthelot
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Adolf von Baeyer
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Robert Bunsen
A
Correct answer
Explanation
Barbital was first synthesized in 1902 by German chemists Emil Fischer and Joseph von Mering. They published their discovery in 1903 and it was marketed in 1904 by the Bayer company as “Veronal”.