Chemistry · Biology
Pharmacology and Therapeutics
1,699 Questions
Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.
Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests
Pharmacology and Therapeutics Questions
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Captopril
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Carbazole
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Hemiaminal
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Carbofuran
A
Correct answer
Explanation
Captopril is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and some types of congestive heart failure.
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Allyl chloride
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Amido black 10B
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4-Aminobenzoic acid
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Aminophylline
D
Correct answer
Explanation
Aminophylline is a bronchodilator. It is a compound of the bronchodilator theophylline with ethylenediamine in 2:1 ratio. The ethylenediamine improves solubility, and the aminophylline is usually found as a dihydrate.
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Amobarbital
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Amoxicillin
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Amphetamine
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Amyl nitrate
A
Correct answer
Explanation
Amobarbital is a drug that is a barbiturate derivative. It has sedative-hypnotic and analgesic properties. It is a white crystalline powder with no odour and a slightly bitter taste.
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Iminodiacetic acid
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Aminoethylpiperazine
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Mesalazine
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Amiodarone
D
Correct answer
Explanation
Amiodarone is an antiarrhythmic agent (medication used for irregular heart beat) used for various types of tachyarrhythmias (fast forms of irregular heart beat), both ventricular and supraventricular (atrial) arrhythmias.
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Benzamide
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Ethenzamide
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Salicylamide
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Alizapride
B
Correct answer
Explanation
Ethenzamide is a common analgesic and anti-inflammatory drug that is used for the relief from fever, headaches, and other minor aches and pains. It is a major ingredient in numerous cold and flu medications and many prescription analgesics.
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Mocetinostat
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Raclopride
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Aziridines
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Benzanthrone
D
Correct answer
Explanation
Benzanthrone is an aromatic hydrocarbon derivate used as a dyestuff intermediate for anthraquinone-based dyes. It has the appearance of a light yellow to brown-green powder with melting point of 170 °C. It is insoluble in water and soluble in alcohol.
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allergy
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angina pectoris
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nephritis
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goitre
A
Correct answer
Explanation
Anti histamin relieves allergy.
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Cannabis sativa
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Erythroxylon coca
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Papaver somniferum.
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Claviceps perpurata
C
Correct answer
Explanation
Morphine is obtained from Papaver somniferum.
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cytochrome
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alpha 1-antitrypsin
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NADH dehydrogenase
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monoamine oxidase
A
Correct answer
Explanation
Cyanide inhibits cytochrome c oxidase (Complex IV) in the mitochondrial electron transport chain, blocking cellular respiration. This prevents ATP production and leads to cellular asphyxiation. Alpha 1-antitrypsin is a protease inhibitor, NADH dehydrogenase is Complex I, and monoamine oxidase breaks down neurotransmitters.
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linear
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trigonal planar
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tetrahedral
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square planar
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octahedral
D
Correct answer
Explanation
In square planar complexes, the geometry is prevalent for transition metal complexes with d8 configuration. Thus, the central atom (Pt) in carboplatin has dsp2 hybridisation with square planar geometry.
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Chlorotrianisene, estrone, estriol
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Diethylstilbestrol, estrone, fosfestrol
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Estriol, diethylstilbestrol, fosfestrol
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Chlorotrianisene, diethylstilbestrol, fosfestrol
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Estrone, estriol, fosfestrol
D
Correct answer
Explanation
Chlorotrianisene is a non-steroidal synthetic oestrogen that was formerly used for the treatment of menopause, deficiencies in ovary function, and prostate cancer.
Diethylstilbestrol is a synthetic nonsteroidal oestrogen that was first synthesized in 1938.
Fosfestrol is a synthetic oestrogen used as an antineoplastic agent.
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bolus
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injection
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insufflation
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sublingual
D
Correct answer
Explanation
Sublingual refers to the pharmacological route of administration by which drugs diffuse into the blood through tissues under the tongue. Many pharmaceuticals are designed for sublingual administration, including cardiovascular drugs, steroids, barbiturates, enzymes, and increasingly, vitamins.
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antihistamine
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antipsychotic
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beta blockers
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dissociatives
C
Correct answer
Explanation
Beta blockers are a class of drugs used for various indications, but particularly for the management of cardiac arrhythmias, cardioprotection after myocardial infarction (heart attack), and hypertension.
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Carisoprodol
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Zaleplon
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Zolpidem
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Zopiclone
A
Correct answer
Explanation
Carisoprodol is a centrally-acting skeletal muscle relaxant. Carisoprodol is slightly soluble in water and freely soluble in alcohol, chloroform and acetone.