Biology

Molecular Biology and Genetics

717 Questions

Molecular biology and genetics explore the structure and function of DNA, RNA, genetic mutations, and heredity. Understanding these building blocks of life is essential for most biology examinations. Review these practice questions to test your molecular genetics knowledge.

DNA structure and basesGenetic mutationsNucleic acids compositionDNA sequencing and replication

Molecular Biology and Genetics Questions

Multiple choice
  1. A nitrogen base, a pentose sugar and a phosphate molecule

  2. A nitrogen base and a phosphate molecule

  3. A pentose sugar and a phosphate molecule

  4. A nitrogen base and a pentose sugar

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

The nucleoside differs from nucleotide in lacking phosphate molecule.

Multiple choice
  1. A double stranded DNA

  2. A single stranded DNA

  3. Histones and RNA

  4. Histone and non-histones

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

It is the nucleoid which is a circular DNA of prokaryotes.

Multiple choice
  1. Denture

  2. Deoxyribonucleic Acid

  3. Ribonucleic Acid

  4. Dinitric Acid

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

DNA stands for Deoxyribonucleic Acid. It is the molecule that carries genetic instructions for the development, functioning, growth, and reproduction of all known organisms.

Multiple choice
  1. Satellite DNA are located on 1, 9, 16 & Y chromosomes.

  2. Satellite DNA does not have spacer sequences.

  3. Satellite DNA are organized as minute clusters of base pairs in the heterochromatic region of chromosomes.

  4. Satellite DNA shows exceptional variability among individuals.

  5. Satellite DNA are of lower density.

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Satellite DNA are organized as large clusters upto 100 million base pairs in the heterochromatic region of chromosomes near centromeres & telomeres, these are also found abundantly on Y chromosomes.

Multiple choice
  1. The amount of noncoding DNA varies greatly among species.

  2. Acts as a genetic switch.

  3. Controls the flow of transcription.

  4. Prevents frameshift mutation.

  5. The noncoding regions are under poor evolutionary pressure and negative selection.

Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

Many noncoding DNA sequences have important biological functions as indicated by comparative genomics studies that report some regions of noncoding DNA that are highly conserved, sometimes on time-scales representing hundreds of millions of years, implying that these noncoding regions are under strong evolutionary pressure and positive selection. 

Multiple choice
  1. UV-B light

  2. UV-A light

  3. Vinyl chloride

  4. Ionising radiation

  5. High tempretures

Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

Thermal disruption at elevated temperature increases the rate of depurination (loss of purine bases from the DNA backbone) and single-strand breaks. For example, hydrolytic depurination is seen in the thermophilic bacteria, which grows in hot springs at 40-80 °C.