Biology
Molecular Biology and Genetics
717 Questions
Molecular biology and genetics explore the structure and function of DNA, RNA, genetic mutations, and heredity. Understanding these building blocks of life is essential for most biology examinations. Review these practice questions to test your molecular genetics knowledge.
DNA structure and basesGenetic mutationsNucleic acids compositionDNA sequencing and replication
Molecular Biology and Genetics Questions
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Conserved sequences
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International Nucleotide Sequence Database Collaboration
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Linguistic sequence complexity
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Sequence hypothesis
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Nucleic acid sequence
A
Correct answer
Explanation
This option is correct. Conserved sequences are identical sequences that occur within nucleic acid sequences, peptide sequences, protein structures and polysaccharides across species or within different molecules, produced by the same organism.
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Glycol nucleic acid
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In silico PCR
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Locked nucleic acid
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Nucleic acid analogue
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UCbase
A
Correct answer
Explanation
This option is correct. Glycol nucleic acid is a polymer identical to DNA or RNA but differing in the composition of its backbone. DNA and RNA have a deoxyribose and ribose sugar backbone, respectively. GNA's backbone is composed of repeating glycol units linked by phosphodiester bonds.
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A and R both are correct and R is the correct explanation of A.
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A and R both are correct and R is not the correct explanation of A.
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A is correct and R is incorrect.
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A is incorrect and R is correct.
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A and R both are incorrect.
A
Correct answer
Explanation
Purines can hydrogen bond only with pyrimidines, where pyrimidine-pyrimidine pairing is energetically unfavorable because the molecules are too far apart for H-bonding to be formed. Thus, this option is correct.
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Only 1
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Only 2
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Only 3
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Only 1 and 2
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Only 2 and 3
A
Correct answer
Explanation
This option is correct. Wobble base pair is a pairing between two nucleotides in RNA molecules that do not follow Watson-Crick base pair rules. The four main wobble base pairs are guanine-uracil (G-U), hypoxanthine-uracil (I-U), hypoxanthine-adenine (I-A) and hypoxanthine-cytosine (I-C).
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Xeno nucleic acid
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Pluramycin A
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k-mer
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L-ribonucleic acid
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Aminoallyl nucleotide
A
Correct answer
Explanation
This option is correct. Xeno nucleic acid is a synthetic alternative to the natural nucleic acids DNA and RNA as an information-storing biopolymer that differs in the sugar backbone.
Match the following.
| |
|
| Column – I |
Column – II |
| A. Peptide nucleic acid |
1. Modified RNA nucleotide synthesised by the group of Jesper Wengel |
| B. Locked nucleic acid |
2. Artificial genetic polymer invented by Albert Eschenmoser |
| C. Threose nucleic acid |
3. Artificially synthesised polymer similar to DNA or RNA invented by Peter E. Nielsen |
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A - 1, B - 2, C - 3
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A - 3, B - 1, C - 2
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A - 2, B - 3, C - 1
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A - 2, B - 1, C - 3
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A - 3, B - 2, C - 1
B
Correct answer
Explanation
This option is correct because all nucleic acids are correctly matched.
Peptide nucleic acid is an artificially synthesised polymer similar to DNA or RNA invented by Peter E. Nielsen.
A locked nucleic acid is a modified RNA nucleotide synthesised by the group of Jesper Wengel.
Threose nucleic acid is an artificial genetic polymer invented by Albert Eschenmoser.
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ACG, CTA, CTA
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GTC, AGC, CTC
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CAG, UCG, GAU
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GAC, TAG, CTA
C
Correct answer
Explanation
The non-template strand of DNA double helix has complementary base pair from template strand. The non-template strand has same sequence as in m-RNA but thymine is replaced by uracil here.
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hydrogen bond
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peptide bond
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glycosidic bond
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phosphodiester bond
C
Correct answer
Explanation
Pentose sugar is linked to nitrogen base glycosidic bond not by glycosidic bond.
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isoleucine
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valine
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lysine
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methionine
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None of these
C
Correct answer
Explanation
Lysine possesses the special codons AAA and AAG.
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RNA
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chromosomes
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genes
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peptides
C
Correct answer
Explanation
Genes - Functional segments of DNA are called genes which regulates the process of development of a cell. Functional segments mean that the information encoded within the DNA structure of a gene directs the manufacture of proteins that carry out life supporting activities.
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Deoxyribonucleic Acid
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Dioxyribonucleic Acid
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Diribonucleic Acid
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Deribonucleic Acid
A
Correct answer
Explanation
Deoxy - Removal of oxygen DNA is the genetic material found in all living organisms. Functional unit of DNA is called genes which regulates the process of development of a cell. All characters of individual are dependent on the types of genes. DNA is made up of deoxyribose sugar which is a fine carbon sugar (one atom of oxygen is removed from the ribose sugar). It also consists of nucleic acid. Nucleic acid are made up of bases, sugar and phosphate group. Bases are of 4 types in DNA consisting of Adenine (A), Thymine (T), Guanine (G) and Cytosine (C).(B), (C) and (D) are wrong terms.
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Adenine
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Guanine
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Thymine
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Uracil
C
Correct answer
Explanation
RNA contains the nitrogenous bases adenine, guanine, cytosine, and uracil. Thymine is found in DNA, not RNA, where it is replaced by uracil.
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Nitrogenous base
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Phosphate group
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Pentose sugar
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None of these
B
Correct answer
Explanation
A nucleoside is a compound that contains a nitrogenous-base bound to a deoxyribose or a ribose sugar.It does not contain phosphate group. It occurs when nucleic acids are hydrolyzed or broken down.
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Monosaccharides
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Nucleotide
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Amino acids
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Fatty acids
B
Correct answer
Explanation
Nucleotides are the single units that make up nucleic acids like RNA and DNA - literally the building blocks of life.A nucleotide is the monomer structural unit of nucleotide chains that form the nucleic acids RNA and DNA, as well as several lesser nucleic acids. The nucleotide consists of a heterocyclic nucleobase, a pentose sugar like ribose or deoxyribose, and a phosphate or polyphosphate group.
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Hexose sugar
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Pentose sugars
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Nitrogenous bases
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Phosphate group
A
Correct answer
Explanation
Sugars that contain 6 carbon atoms in their structure are called hexose sugars. Glucose, galactose, and mannose are aldoses are the examples of hexoses.