Multiple choice

Which of the following is the protein governing the coordination of cell–cell adhesion and gene transcription in mammals?

  1. Alpha-catenin

  2. Beta-catenin

  3. Delta-2-catenin

  4. Gamma-catenin

  5. Gelsolin
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

It is a dual function protein, regulating the coordination of cell–cell adhesion and gene transcription. Mutations and overexpression of β-catenin are associated with many cancers, including hepatocellular carcinoma, colorectal carcinoma, lung cancer, malignant breast tumors, ovarian and endometrial cancer.

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