Biology

Human Immunity and Blood

2,096 Questions

Human immunity and blood questions cover the physiological mechanisms protecting the body against diseases and the components of blood. Topics include blood groups, cell mediated immunity, monoclonal antibodies, and blood coagulation. These biology topics frequently appear in general science sections of competitive exams.

Blood groupsCell mediated immunityMonoclonal antibodiesBlood coagulationCancer immunology

Human Immunity and Blood Questions

Multiple choice bio-chemistry immunity and blood groups active and passive immunity acquired immunity innate and acquired immunity

The major difference between humoral immunity and cell-mediated immunity is that:

  1. humoral immunity is non-specific, whereas cell-mediated immunity is specific for particular antigens

  2. the agents of humoral immunity are carried in the bloodstream, whereas the cells of the latter are concentrated in lymph nodes

  3. humoral immunity cannot function independently; it is always activated by cell-mediated immunity

  4. humoral immunity acts against free-floating antigens, whereas cell-mediated immunity works against pathogens that. have entered body cells

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

The immune system has two divisions-humoral immunity and cell-mediated immunity. The humoral immunity protects against extracellular pathogens while the cell-mediated immunity protects against intracellular pathogens.

so, the correct option is 'humoral immunity acts against free-floating antigens, whereas cell-mediated immunity works against pathogens that have entered body cells'.

Multiple choice bio-chemistry immunity and blood groups active and passive immunity acquired immunity innate and acquired immunity

The cells that actually release antibodies are

  1. Helper T-cells

  2. Cytotoxic T-cells

  3. Plasma cells

  4. Suppressor cells

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Activated B cells differentiate into either antibody-producing cells called plasma cells that secrete soluble antibody or memory cells that survive in the body for years afterwards in order to allow the immune system to remember an antigen and respond faster upon future exposures.

So, the correct option is 'Plasma cells'.

Multiple choice bio-chemistry immunity and blood groups active and passive immunity acquired immunity innate and acquired immunity

Control of the activated complement components results from

  1. Agglutination

  2. Immune adherence

  3. Instability and inactivation of some of these components

  4. Mobility of phagocytes

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

The activity of complement components is modulated by a system of regulatory proteins that prevent tissues damage as a result of inadvertent binding of activated complement components to host cells or spontaneous activation of complement components in plasma.

So, the correct option is 'instability and inactivation of some of these components'.

Multiple choice bio-chemistry diseases and immunity antibodies antibodies and antitoxin antigen and antibody

Lysis of foreign cells is mediated through

  1. IgM only

  2. IgA only

  3. IgM and IgG

  4. IgD and IgE

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation
  • Immunoglobulin M (IgM) is one of several forms of the antibody that are produced by vertebrates. IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. IgM can bind to complement component and activate the classical pathway, leading to opsonization of antigens and cytolysis (lysis of foreign cells).
  • IgG is the most common type of antibody found in blood circulation. IgG molecules are created and released by plasma B cells. Coating of IgG on pathogen surfaces (known as opsonization) allows their recognition and ingestion by phagocytic immune cells leading to the lysis of foreign cells.
So, the correct answer is 'IgM and IgG'.
Multiple choice bio-chemistry diseases and immunity antibodies antibodies and antitoxin antigen and antibody

Antibodies are formed by

  1. T-cells

  2. Monocytes

  3. Phagocytes

  4. B-cells

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Antibody are produced by B-lymphocytes. The plasma cell /plasma B cells/effector B cell are white blood cells that secrete large volumes of antibodies. Plasma cell originates in the bone marrow.B cell differentiate into a plasma cell that produces antibody molecules. These are transported by the blood plasma and the lymphatic system. Once these are released into the blood and lymph, these antibody molecules bind to the target antigen and initiate its neutralization or destruction.

So, the correct answer is 'B-cells'.

Multiple choice bio-chemistry diseases and immunity antibodies antibodies and antitoxin antigen and antibody

Immunoglobulins (antibodies) are basically

  1. Lipoproteins

  2. Phospholipids

  3. Glycoproteins

  4. Nucleoproteins

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Immunoglobulins, also known as antibodies, are glycoprotein molecules produced by plasma cells (white blood cells). They act as a critical part of the immune response by specifically recognising and binding to particular antigens, such as bacteria or viruses, and aiding in their destruction. So, the correct option is 'Glycoproteins'

Multiple choice bio-chemistry diseases and immunity antibodies antibodies and antitoxin antigen and antibody

Which statement is correct?

  1. Antibodies are formed by mast cells

  2. B-lymphocytes are matured in thymus

  3. Histamine acts as inflamatory mediator

  4. CMI is mediated by B-lymphocytes

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Mast cells are coated with IgE, which is produced by plasma cells (the antibody-producing cells of the immune system). IgE antibodies are typically specific to one particular antigen. In allergic reactions, mast cells remain inactive until an allergen binds to IgE already coated upon the cell.

So, the correct option is 'Antibodies are formed by mast cells'.

Multiple choice bio-chemistry diseases and immunity antibodies antibodies and antitoxin antigen and antibody

................  is associated with allergic reactions

  1. IgE

  2. IgG

  3. IgA

  4. IgM

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Antibodies are the immunoglobulins which are produced in response to the antigen. The immunoglobulin E antibodies or IgE binds to an allergen and trigger the release of inflammatory chemicals such as histamine.
Therefore, the correct answer is option A.

Multiple choice bio-chemistry diseases and immunity antibodies antibodies and antitoxin antigen and antibody

Antibodies are secreted by

  1. T-lymphocytes

  2. B-lymphocytes

  3. Both A and B

  4. Natural killer cell

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

An antibody or immunoglobulin is a  proteinaceous compound produced mainly by differentiated plasma cells i.e., B lymphocytes. It is used by the immune system to identify and neutralize pathogens such as bacteria and viruses. Thus, the correct answer is option B.

Multiple choice bio-chemistry diseases and immunity antibodies antibodies and antitoxin antigen and antibody

Antibodies in are complex

  1. Prostaglandins

  2. Glycoproteins

  3. Lipoproteins

  4. Steroids

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

An antibody is a protein which is produced in response to the antigen by the plasma cells. Antibodies are $\gamma$-globulin proteins that have sugar groups attached to amino acid chains. They can be classified as glycoproteins. These are y-shaped. So, the correct answer is option B.

Multiple choice bio-chemistry diseases and immunity antibodies antibodies and antitoxin antigen and antibody

The cells that actually release the antibodies are

  1. Helper T-cells

  2. Cytotoxic T-cells

  3. Plasma cells

  4. Memory cells

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Plasma cells, also known as plasma B cells or plasmocytes are white blood cells that secrete large volumes of antibodies. They are transported by the blood plasma and the lymphatic system. Plasma cells are originated in the bone marrow, B cells differentiate into plasma cells that produce antibody molecules. Once released into the blood and lymph, these antibody molecules bind to the target antigen (foreign substance) and initiate its neutralization or destruction.

So, the correct answer is 'Plasma cells'.

Multiple choice bio-chemistry diseases and immunity antibodies antibodies and antitoxin antigen and antibody

Lysis of foreign cells is mediated through 

  1. IgM and IgG

  2. IgG and IgA

  3. IgA and IgD

  4. IgD and IgE

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

  • Immunoglobulin M (IgM) is one of several forms of the antibody that are produced by vertebrates. 
  • IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. 
  • IgM can bind to complement component and activate the classical pathway, leading to opsonization of antigens and cytolysis (lysis of foreign cells).
  • IgG is the most common type of antibody found in blood circulation. IgG molecules are created and released by plasma B cells. 
  • Coating of IgG on pathogen surfaces (known as opsonization) allows their recognition and ingestion by phagocytic immune cells leading to the lysis of foreign cells.
So, the correct answer is 'IgM and IgG'.

Multiple choice bio-chemistry diseases and immunity antibodies antibodies and antitoxin antigen and antibody

B-cells produce antibodies in response to instruction received from 

  1. Killer T-cells

  2. Suppressor T-cells

  3. Mast cells

  4. Helper T-cells

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

B cells, also known as B lymphocytes are a type of white blood cell of the lymphocyte subtype. They function in the humoral immunity component of the adaptive immune system by secreting antibodies. B-cells bind to an antigen, receive help from a cognate helper T cell and differentiate into a plasma cell that secretes large amounts of antibodies.

So, the correct answer is 'Helper T-cells'.