Biology
Human Immunity and Blood
2,051 Questions
Human immunity and blood questions cover the physiological mechanisms protecting the body against diseases and the components of blood. Topics include blood groups, cell mediated immunity, monoclonal antibodies, and blood coagulation. These biology topics frequently appear in general science sections of competitive exams.
Blood groupsCell mediated immunityMonoclonal antibodiesBlood coagulationCancer immunology
Human Immunity and Blood Questions
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Peanuts, cockroach parts, eggs.
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Mold spores, animal dander, pollen
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Seafood, Tomatoes, dust mites
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All of the above
D
Correct answer
Explanation
All three option groups (A, B, C) contain valid allergens from different categories: peanuts/eggs/seafood are food allergens; mold/pollen/dust mites are airborne allergens; cockroach parts and animal dander are indoor allergens. Since each option lists valid examples of allergen types, 'All of the Above' correctly encompasses all categories mentioned in the question.
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O ; AB
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O- ; AB-
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O+ ; AB+
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O- ; AB+
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O+ ; AB-
D
Correct answer
Explanation
Blood group O- is the universal donor because it lacks A, B, and Rh antigens. Blood group AB+ is the universal receiver because it has A, B, and Rh antigens, meaning it does not produce antibodies against them.
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An ‘Allogeneic’ blood transfusion means that the donor and recipient are the same.
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An ‘Autologous’ blood transfusion means that the donor and recipient are two different individuals.
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Donated blood intended for use in an individual other than the blood donor is called a 'Homologous' blood transfusion
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Donating blood can reduce the life of a person
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The scientific term for blood donation
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Fatigue experienced after blood donation
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Blood donation where specific components of blood are separated and transfused
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Period during which a person is prohibited from donating blood
C
Correct answer
Explanation
Apheresis is a medical technology in which the blood of a person is passed through an apparatus that separates out one particular constituent and returns the remainder to the circulation.
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Yes
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No
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Yes, if not dependent on insulin injections
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Not Possible
C
Correct answer
Explanation
Diabetics who manage their condition through diet or oral medication (not insulin) are generally eligible to donate blood, provided the condition is well-controlled. Insulin-dependent diabetics are usually deferred because of the stricter medical monitoring required and potential complications.
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Blood
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Bone marrow
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Lymph nodes
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None of the above
A,B,C
Correct answer
Explanation
Hematological malignancies (blood cancers) affect the blood, bone marrow, and lymphatic system including lymph nodes. These cancers include leukemias, lymphomas, and myelomas which originate in these tissues and disrupt normal blood cell production. Blood, bone marrow, and lymph nodes are all integral parts of the hematopoietic system.
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Blood
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Bone marrow
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Liver
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All the above
A,B
Correct answer
Explanation
Hematological malignancies are cancers of the blood-forming tissues, primarily blood and bone marrow. Blood (A) and bone marrow (B) are correct as they are the sites of blood cell production and maturation. Liver (C) is not a hematological organ, and D (All the above) would only be correct if C were also correct.
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Chronic lymphocytic leukemia
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Chronic myelogenous leukemia
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Both the options
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None of the above
C
Correct answer
Explanation
Both Chronic Lymphocytic Leukemia (CLL) and Chronic Myelogenous Leukemia (CML) are cancers of white blood cells. CLL affects the lymphoid lineage while CML affects the myeloid lineage, but both involve malignant proliferation of white blood cells.
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Rapid increase of WBC
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Rapid increase of immature blood cells
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Rapid increase of RBC
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All the above
B
Correct answer
Explanation
Acute leukemia is characterized by rapid proliferation of immature blast cells in the bone marrow. While white blood cell count may be elevated, the defining feature is the accumulation of immature, non-functional cells (blasts) rather than just an increase in normal WBCs or RBCs.
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Hairy cell leukemia
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Aleukemia
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T-Cell leukemia
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All the above
B
Correct answer
Explanation
Aleukemic leukemia is a specific condition where leukemic cells are present in the bone marrow but do not significantly circulate in peripheral blood, resulting in normal or low white blood cell counts on routine blood tests. This makes detection challenging without bone marrow examination.
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A&O groups
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Only O group
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A&B groups
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All groups
B
Correct answer
Explanation
Blood group O individuals can ONLY receive blood from other O group individuals because they have both anti-A and anti-B antibodies in their plasma. Receiving A or B blood would cause a dangerous transfusion reaction. While O is called the 'universal donor' (can give to anyone), they can only receive from other O donors. This is fundamental transfusion medicine.
A
Correct answer
Explanation
Leukemia is a cancer of the body's blood-forming tissues, including the bone marrow and lymphatic system. It specifically involves abnormal production of white blood cells, which is correctly stated in this question.
B
Correct answer
Explanation
The ELISA test stands for Enzyme-Linked Immunosorbent Assay, which is used to detect antibodies, antigens, or proteins in samples such as blood or serum, rather than counting or detecting red blood cells. Red blood cell counts are typically done via a complete blood count or hemogram. Therefore, the statement is false.
C
Correct answer
Explanation
Type O blood is the most common blood type globally, with O positive and O negative making up nearly half of the world's population. O negative is particularly valuable as the universal donor for emergency transfusions. A, B, and AB are less prevalent.
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10 million
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12 million
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5 million
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7 million
A
Correct answer
Explanation
The bone marrow is remarkably productive, manufacturing approximately 10 million red blood cells every second to maintain normal blood counts. This continuous production is essential because red blood cells have a lifespan of only about 120 days. The body must constantly replenish its supply to ensure adequate oxygen transport throughout the body.