Biology
Human Immunity and Blood
2,051 Questions
Human immunity and blood questions cover the physiological mechanisms protecting the body against diseases and the components of blood. Topics include blood groups, cell mediated immunity, monoclonal antibodies, and blood coagulation. These biology topics frequently appear in general science sections of competitive exams.
Blood groupsCell mediated immunityMonoclonal antibodiesBlood coagulationCancer immunology
Human Immunity and Blood Questions
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Antibodies
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Antigens
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Antioxidants
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Antiquity
B
Correct answer
Explanation
Blood groups A, B, AB, and O are classified based on antigens present on red blood cells. Type A has A antigens, Type B has B antigens, Type AB has both, and Type O has neither. Antibodies in plasma determine compatibility, but antigens on RBCs define the type.
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Platelets
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Red blood cells
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Lymph nodes
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White blood cells
A
Correct answer
Explanation
Platelets (thrombocytes) are cell fragments responsible for blood clotting. They form plugs at injury sites and release clotting factors. Red blood cells transport oxygen, white blood cells fight infection, and lymph nodes are immune system organs - none of these handle clotting.
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your body will not create antibodies for any of the other blood groups
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you can give blood to people having blood groups A and B
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you can receive blood only from people having blood groups A and B
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your body will create antibodies for all of the other blood groups
A
Correct answer
Explanation
Blood group AB individuals have both A and B antigens on their RBCs, so they don't produce anti-A or anti-B antibodies. This makes them universal recipients. Option A correctly states this, though they can receive from A, B, AB, and O donors, not just A and B.
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Allergies
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Isotopes
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Antigens
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Antibodies
C
Correct answer
Explanation
The immune system protects the body against antigens, which are foreign substances like bacteria, viruses, or toxins that trigger an immune response. Allergies are hypersensitive immune reactions to harmless substances, isotopes are variants of chemical elements unrelated to immunity, and antibodies are proteins produced by the immune system to fight antigens (not what the system protects against).
C
Correct answer
Explanation
AB blood group is called the universal recipient because individuals with AB type have both A and B antigens on their red blood cells and no anti-A or anti-B antibodies in their plasma. This allows them to receive blood from any group (A, B, AB, or O) without adverse reactions. O+ is the universal donor for positive blood types only.
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Kolkata blood group
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Bombay Blood group
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AB -ve
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B -ve
B
Correct answer
Explanation
The Bombay Blood Group (hh phenotype) is the rarest blood type in the world, occurring in approximately 1 in 10,000 people in India and 1 in 1,000,000 globally. It lacks H antigens and can cause severe transfusion reactions if mismatched with ABO types.
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Liver
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Bone Marrow
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Kidneys
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Heart
B
Correct answer
Explanation
Red blood cells (erythrocytes) are produced in the bone marrow through hematopoiesis. In adults, this primarily occurs in the flat bones (sternum, ribs, pelvis). The liver produces RBCs in fetuses, and kidneys produce erythropoietin that stimulates RBC production, but don't make the cells themselves.
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Brain
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Heart
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Bone marrow
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Pancreas
C
Correct answer
Explanation
Red blood cells, along with most other blood cells, are primarily produced in the spongy tissue inside bones known as bone marrow. In adults, this hematopoiesis occurs mainly in the marrow of large bones such as the vertebrae, ribs, and sternum.
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Brain
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Heart
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Bone marrow
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Pancreas
C
Correct answer
Explanation
Red blood cells are continuously produced in the bone marrow of humans and other vertebrates through a process called erythropoiesis. The brain, heart, and pancreas serve entirely different vital functions and are not sites of blood cell formation.
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A&O groups
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Only O group
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A&B groups
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All groups
B
Correct answer
Explanation
Blood group O individuals can only receive from O group because they have both anti-A and anti-B antibodies. They are universal donors but can only accept from their own type.
B
Correct answer
Explanation
While Type O is indeed the most common blood type globally, the existence of 'Type A-H' as a legitimate blood type is questionable. The standard ABO system includes A, B, AB, and O - not A-H.
B
Correct answer
Explanation
AB positive blood group individuals are universal recipients - they can receive blood from any blood group (A, B, AB, or O) because they have both A and B antigens and no anti-A or anti-B antibodies in their plasma.
B
Correct answer
Explanation
Leukemia is a cancer of the body's blood-forming tissues, including the bone marrow and the lymphatic system. It involves abnormal production of white blood cells, making it fundamentally a blood disease.
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Liver
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Bone Marrow
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Kidneys
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Heart
B
Correct answer
Explanation
Red blood cells (erythrocytes) are produced in the bone marrow through erythropoiesis, primarily in the flat bones like sternum, pelvis, ribs, and vertebrae. The liver, kidneys, and heart have other essential functions but don't produce RBCs.
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Any blood type
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Only other O+ blood types.
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Any blood type that is RH+.
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AB+ only
C
Correct answer
Explanation
O+ blood can be donated to any Rh-positive recipient (A+, B+, AB+, O+) because it lacks A and B antigens but has the Rh factor. It cannot be given to Rh-negative recipients as they would react to the Rh protein. The Rh+ factor means O+ can only go to other positive blood types.