Multiple choice

The synthesis of an immunoglobulin in either a secretory or membrane bound form is governed by

  1. allelic exclusion

  2. class switching

  3. differential RNA processing

  4. affinity maturation

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

The choice between expressing an immunoglobulin as a membrane-bound B-cell receptor or as a secreted antibody is determined by differential RNA processing and alternative polyadenylation of the heavy chain primary transcript, rather than DNA rearrangement events like class switching.