Multiple choice

On daignosis it was found that Mr. Batra is suffering from pernicious anemia. Which of the following antibodies are of most use for the diagnosis of pernicious anemia in an individul?

  1. Anti-parietal cell

  2. Anti-thyroid peroxidase

  3. Anti-nuclear antibodies

  4. Anti-IgG Fc

  5. Anti-TSH receptors

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A Correct answer
Explanation

Parietal cell antibodies detected by immunofluorescence on stomach sections are important markers of inflammatory atrophic gastritis and the subsequent pernicious anemia which can develop. Antibodies to intrinsic factors are even stronger confirmation.