Multiple choice

Which of the following statements about gastric parietal cell antibodies [GPC] is true?

  1. GPC are found more frequently in gastric juice than in serum.

  2. GPC are diagnostic of pernicious anaemia.

  3. They are considered best in screening test for pernicious anaemia.

  4. They inhibit absorption of vitamin B12 in the ileum.

  5. They are usually of IgM isotype.
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

As they are not specific for pernicious anaemia, GPC must be interpreted in conjunction with low serum vitamin B12 level.

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