Multiple choice

A young lady is suffering from Pernicious anaemia, which is an autoimmune disorder in which the body fails to make sufficient RBCs. Which of the following antibodies is/are of most use for the diagnosis of pernicious anaemia in such people?

  1. Anti-parietal cells

  2. Anti-thyroid peroxidase

  3. Anti-nuclear

  4. Anti-IgG Fc

  5. Anti-TSH receptor

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A Correct answer
Explanation

Parietal cell antibodies detected by immunofluorescence in stomach sections are important markers of inflammatory atrophic gastritis and subsequent pernicious anaemia.