Multiple choice

Paroxysmal nocturnal hemoglobinuria is a rare, genetically acquired life-threatening disorder. It results from deficiency in which of the following?

  1. Myeloperoxidase

  2. Decay accelerating factor (DAF)

  3. Classical pathway C components

  4. C1 inhibitor

  5. C8

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

The spontaneous creation of alternative pathway C3 convertase on the red cell is normally eliminated through membrane bound DAF.