Multiple choice Defects in neutrophil NADPH oxidase system produces ________________. chronic granulomatous disease chediak-higashi disease leukocyte adhesion deficiency hashimoto's disease streptococcal infection Reveal answer Fill a bubble to check yourself A Correct answer Explanation There is a failure to make reactive oxygen intermediates and to raise the pH in the phagocytic vacuole, which facilitates microbicidal action.