Multiple choice

ATP is produced in mitochondria as a result of oxidative phosphorylation and transferred to the cytoplasm but inner membrane of mitochondria is impenetrable to charged species. Two transport systems are used for transferring Pi and ADP into the matrix. ATP is transferred to the cytosol.

What is the function of ATP synthase?

  1. It is used for catalysing reversibly the formation of l-malic acid from glyoxylate and acetyl-CoA.

  2. It transfers one H+ and one H2PO4- into matrix.

  3. It reduces oxaloacetate to malate in gluconeogenesis.

  4. It acts as the catalyst during isomerisation of ribulose 5-phosphate to ribose 5-phosphate.

  5. It acts as the catalyst to form ATP using ADP and Pi.
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E Correct answer
Explanation

ATP synthase is a complex mitochondrial enzyme that is enclosed in a membrane. It acts as the catalyst to form ATP from ADP and Pi and also helps to transfer protons from positive side (intermembrane space) to the negative side (matrix) of the membrane.

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