Multiple choice

Viral antigen shift involves which of the following changes?

  1. Single point mutation.

  2. Random point mutations.

  3. Interchange of large segments of the viral genome with other viruses.

  4. Rearrangement of the viral structural architecture.

  5. Regression to an earlier variant.
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C Correct answer
Explanation

The ability to interchange large segments of the genome with a viral reservoir in other animal species is the basis of antigenic shift leading to radical change in antigen, particularly crucial antigens giving protective immunity such as the viral hemagglutinin.

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