Multiple choice

Mutations which alter nucleotide sequence within a gene are

  1. frame shift mutations

  2. base pair substitutions

  3. Both (1) and (2)

  4. None of these
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A Correct answer
Explanation

Gene mutation or point mutation is the result of a change in the nucleotide sequence of the DNA molecule in a particular region of the chromosome. Gene mutation occurs in the form of duplication, insertion, deletion, inversion or substitution of bases. The addition or deletion of a base may change the reading frame of nucleotide sequence. This is called frame-shift mutation.

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