Multiple choice

The thyroid gland of the body becomes overactive in

  1. Giant-cell arteritis

  2. Glomerulonephritis

  3. Goodpasture's syndrome

  4. Graves' disease

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D Correct answer
Explanation

Graves' disease is an autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones (a serious metabolic imbalance known as hyperthyroidism and thyrotoxicosis). This is caused by autoantibodies (TSHR-Ab) that activate the TSH-receptor (TSHR), thereby stimulating thyroid hormone synthesis and secretion, and thyroid growth (causing a diffusely enlarged goiter).

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