Multiple choice

The preintegration complex is essentially the viral core released into the host cell. Which among the following proteins regulates the nuclear import of the HIV-1 pre-integration complex?

  1. Tat

  2. Vif

  3. Nef

  4. Vpr

  5. Rev

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Vpr is a human immunodeficieny viral gene and protein product. Vpr stands for Viral Protein R. It plays an important role in regulating nuclear import of the HIV-1 pre-integration complex and is required for virus replication in non-dividing cells, such as macrophages.