Multiple choice The structural component of HIV required for cell–cell fusion is p2 protein p24 gp 41 gp 120 gp 160 Reveal answer Fill a bubble to check yourself C Correct answer Explanation For the HIV infection to occur the cell fusion is essential. This is done by the transmembrane glycoprotein gp 41. HIV-1 utilizes two major co-receptors along with CD4 to bind to, fuse with, and enter target cells.