Multiple choice

Which of the following statements about mupirocin (a protein synthesis inhibitor) is true?

  1. Mupirocin is a bactericidal drug at low concentrations.

  2. Mupirocin binds to t-RNA synthetase.

  3. Mupirocin is very effective on Propionibacterium acne.

  4. Mupirocin binds to 50S sub-unit of ribosomes.
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

This is the correct answer. Mupirocin reversibly binds to the isoleucyl t-RNA synthetase in Staphylococcus aureus and Streptococcus, resulting in inhibition of protein synthesis.

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