Multiple choice

Match the following items given - which represents inhibitors of bacterial protein synthesis and their functions respectively: Column-I Column-II

  1. Streptomycin A. prevents mRNA translocation along ribosome
  2. Tetracycline B. prevents the activity of peptidyl transferase
  3. Erythromycin C. prevents the initiation of translation
  4. Chloramphenicol D. prevents the interaction between mRNA and tRNA
  5. Neomycin E. prevents aminoacyl tRNA binding to ribosome

  1. 1 - A, 2 - B, 3 - C, 4- D, 5 - E

  2. 1- D, 2 - B, 3 - A, 4 - D, 5 - C

  3. 1 - B, 2 - A, 3 - D, 4 - C, 5 - E

  4. 1 - E, 2 - A, 3 - B, 4 - D, 5- C

  5. 1 - C, 2 - E, 3 - A, 4 - B, 5 - D
Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

Streptomycin is powerful translation inhibitor due to antibiotic in polyamine-complement bacteria. Tetracycline particularly binds to 30S ribosome of bacteria inhibiting aminoacyl tRNA binding to RNA-ribosome. Erythromycin prevents protein synthesis by exciting isolation of peptidyl-tRNA from ribosomes. Chloramphenicol binds to 23S rRNA of 50S subunt of bacterial ribosome preventing peptidyl transferase. Neomycin prevents 30S subunit of ribosome by inhibiting the interaction between mRNA and tRNA.

Keep practicing — related questions