Multiple choice

Match the three columns List - A (antibiotics), List - B (classes) and List - C (mechanism of action).

   
List - A
List - B
List - C
P. Linezolid 1. carbacephem i. inhibiting translocation of peptidyl-tRNA
Q. Amikacin 2. aminoglycosides ii. inhibiting protein synthesis
R. Cephalexin 3. oxazolidonone iii. inhibiting peptidoglycan layer synthesis
S. Loracarbef 4. first generation cephalosporin iv. inhibiting cell wall synthesis

  1. P - 3 - ii, Q - 2 - i, R - 4 - iii, S - 1 - iv

  2. P - 2 - i, Q - 3 - iv, R - 1 - iii, S - 4 - ii

  3. P - 2 - iii, Q - 3 - ii, R - 1 - i, S - 4 - iv

  4. P - 2 - i, Q - 3 - iv, R - 1 - ii, S - 4 - iii

  5. P - 2 - i, Q - 3 - iv, R - 4 - iii, S - 1 - ii
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Linezolid belongs to oxazolidonone class and this is a Protein synthesis inhibitor that prevents the initiation step. Amikacin belongs to the aminoglycosides. Binding to the bacterial 30S ribosomal subunit inhibits the translocation of the peptidyl-tRNA from the A-site to the P-site. Cephalexin is first generation cephalosporin and It disrupts the synthesis of the peptidoglycan layer of bacterial cell walls. Loracarbef is carbacephem antibiotic. It prevents bacterial cell division by inhibiting cell wall synthesis. Hence, the correct answer using the codes is P - 3 - ii, Q - 2 - i, R - 4 - iii, S - 1 - iv.

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