Multiple choice

Which of the following classes of antibiotics eventually leaves a bacterium unable to synthesise proteins that are vital to its growth by binding to 30S ribosomal unit?

  1. Macrolides

  2. Rifampicins

  3. Aminoglycosides

  4. Lincosamides

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Aminoglycosides bind to bacterial 30S ribosomal unit inhibiting the translocation of the peptidyl-tRNA from the A-site to the P-site and also causing misreading of mRNA, leaving the bacterium unable to synthesise proteins vital to its growth.