Antibiotics (GATE)

Antibiotics (GATE)

14 Questions Published

Questions

Question 1 Multiple Choice (Single Answer)

Which of the following classes of antibiotics eventually leaves a bacterium unable to synthesise proteins that are vital to its growth by binding to 30S ribosomal unit?

  1. Macrolides
  2. Rifampicins
  3. Aminoglycosides
  4. Lincosamides
Question 2 Multiple Choice (Single Answer)

Which of the following aminoglycosides is used for the treatment of gonorrhoea?

  1. Gentamicin
  2. Amikacin
  3. Streptomycin
  4. Spectinomycin
Question 3 Multiple Choice (Single Answer)

Gelandamycin is an anti-tumor antibiotic. It was discovered in

  1. Streptomyces hygroscopicus
  2. Streptomyces griseus
  3. Micromonospora purpurea
  4. Streptomyces tenebrarius
Question 4 Multiple Choice (Single Answer)

Cefadroxil is a broad spectrum first generation antibiotic. It is administered 

  1. intravenously
  2. orally
  3. intradermally
  4. intramuscularly
Question 5 Multiple Choice (Single Answer)

Ertapenem is a broad-spectrum, carbapenem antibiotic. It is effective against which of the following?

a. Methicillin Resistant Staphylococcus aureus (MRSA)
b. Pseudomonas aeruginosa
c. Ampicillin Resistant Enterococci (ARE)
d. Eubacterium lentum

  1. Only a and d
  2. Only a, b and c
  3. Only d
  4. Only c and d
Question 6 Multiple Choice (Single Answer)

Consider the following statements:

A: Cefuroxime is active against Haemophilus influenzae, N. gonorrhoeae and Lyme disease.
B: It is less susceptible to beta lactamases.

  1. A is correct but B is incorrect
  2. A is incorrect but B is correct.
  3. Both A and B are correct but B is not the correct explanation of A
  4. Both A and B are correct and B is the correct explanation of A
Question 7 Multiple Choice (Single Answer)

To increase the effectiveness of cefoperazone against beta-lactamase-producing organisms, it is formulated with which of the following?

  1. Tazobactam
  2. Sulbactam
  3. Tebipenem
  4. Avibactam
Question 8 Multiple Choice (Single Answer)

Third generation cephalosporins are ineffective against Pseudomonas as such. Which of the following pairs of antibiotics is an exception to this characteristic?

  1. Cefoperazone and Ceftibuten
  2. Cefoperazone and Cefpodoxime
  3. Cefoperazone and Ceftazidime
  4. Cefoperazone and Ceftriaxone
Question 9 Multiple Choice (Single Answer)

Vancomycin is a glycopeptide antibiotic used to treat several bacterial infections. Which of the following organisms makes vancomycin?

  1. Bacillus brevis
  2. Streptomyces aureofaciens
  3. Amycolatopsis orientalis
  4. Aggregatibacter actinomycetemcomitans
Question 10 Multiple Choice (Single Answer)

Clindamycin, a lincosamide, is inactive on most Gram-negative rods. For which of the following bacteria is it used as the first-line drug of choice?

  1. Legionella birminghamensis
  2. Pseudomonas argentinensis
  3. Haemophilus influenzae
  4. Capnocytophaga canimorsus
Question 11 Multiple Choice (Single Answer)

Daptomycin is bactericidal against Gram-positive bacteria. Which of the following functions is/are inhibited due to its action?

a. DNA synthesis
b. RNA synthesis
c. Protein synthesis

  1. Only a and c
  2. Only b
  3. Only a and b
  4. All of the above
Question 12 Multiple Choice (Single Answer)

Telithromycin is a ketolide antibiotic. It is especially used to treat

  1. mouth infection
  2. syphilis
  3. pneumonia
  4. Lyme disease
Question 13 Multiple Choice (Single Answer)

Chromobacterium violaceum is a Gram-negative, facultative anaerobic and non-sporing coccobacillus. Which of the following antibiotics produced by this is effective against Gram-negative bacteria?

  1. Aztreonam
  2. Paromycin
  3. Doripenem
  4. Tigecycline
Question 14 Multiple Choice (Single Answer)

Pyrazinamide is only used for the treatment of tuberculosis. Which of the following compounds acts in synergy with it for treatment of latent tuberculosis?

  1. Isoniazid
  2. Rifampicin
  3. Ethambutol
  4. Streptomycin