Tag: gene therapy

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Questions Related to gene therapy

Multiple choice zoology applications of biotechnology gene therapy application of biology in therapy and vaccine gene cloning

Immune deficiency disorder, which occur due to mutation in gene, involved in maturation of T and B lymphocytes is

  1. IDDM

  2. Hashimoto disease

  3. SCID

  4. Pernicious anemia
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

  • Insulin-Dependent Diabetes Mellitus or IDDM is an immune deficiency disorder. It occurs due to a mutation in a gene involved in insulin-producing β cells in the pancreas. 
  • Hashimoto's disease is an autoimmune disorder that results in hypothyroidism. It results in defects in the maturation of T lymphocytes. 
  • Severe combined immunodeficiency (SCID) is an immunodeficiency syndrome. It occurs due to a mutation in the gene involved in the maturation of T and B lymphocytes. 
  • Pernicious anemia is also called as vitamin B$ _{12}$ deficiency syndrome. It results due to a lack of intrinsic factor. 
Thus, the correct answer is 'Hashimoto disease and SCID.'

Multiple choice zoology applications of biotechnology gene therapy application of biology in therapy and vaccine gene cloning

"Introduction of a normal functional gene into cells, in order to replace defective or mutated gene'." is known as 

  1. Biosafety

  2. Biopiracy

  3. Biopatent

  4. Gene therapy
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Introduction of a normal functional gene into cells, in order to replace defective or mutated gene is known as gene therapy. It is also called as gene transfer. It is done to correct genetic disorders. Biosafety is the prevention of large-scale loss of biological integrity. Biopiracy is the practice of exploiting indigenous knowledge of nature, originating with indigenous peoples without compensation to the indigenous people. Biopatent is a patent granted by the government to the inventor of biological entities.

Thus, the correct answer is 'Gene therapy.'

Multiple choice zoology applications of biotechnology gene therapy application of biology in therapy and vaccine gene cloning

a functional ADAcDNA can be introduced into cells of the patients receiving gene therapy by using vector constituted by

  1. E.coil

  2. Reoviridae

  3. Retrovirus

  4. Agrobacterium
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation
The deficiency of the purine salvage enzyme adenosine deaminase is associated with severe B and T-cell dysfunction. In order to investigate the ADA molecule, gene therapy using E.coli, cDNA clones encoding ADA gene sequences are obtained.
So the correct option is 'E.coli'.
Multiple choice zoology applications of biotechnology gene therapy application of biology in therapy and vaccine gene cloning

Cystic fibrosis can be treated by .......... gene therapy.

  1. TGP-B

  2. TPA

  3. DNase

  4. BGH
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

DNase (Deoxyribonuclease) is used in cystic fibrosis treatment to break down the thick mucus in the lungs, which is rich in DNA from dead white blood cells. While gene therapy is a research area for cystic fibrosis, DNase is the standard pharmacological treatment listed.