Tag: diseases and immunity

Quizzes (21) Questions (266)

Questions Related to diseases and immunity

Multiple choice zoology immune system active and passive immunity immunity related disorders and problems diseases and immunity

The graft rejection takes place due to the presence of ________

  1. T cells

  2. B cells

  3. Mast cells

  4. None of the above
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Graft rejection is primarily a cell-mediated immune response where T cells recognize foreign MHC molecules on the transplanted tissue. While other cells participate, T cells are the primary effectors of the rejection process.

Multiple choice zoology immune system active and passive immunity immunity related disorders and problems diseases and immunity

Consider the following four statements (A -D) regarding kidney transplant and select the two options that are true

(A) Even if a kidney transplant is proper the recipient may need to take immuno-suppresants for a long time.

(B) The cell-mediated immune response is responsible for the graft rejection.

(C) The B - lymphocytes are responsible for rejection of the graft.

(D) The acceptance or rejection of a kidney transplant depends on specific interferons.

The two correct statements are

  1. (A) and (B)

  2. (B) and (C)

  3. (C) and (D)

  4. (A) and (D)
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Immunosuppressants are drugs/medicines that lower the immune system's ability to reject a transplanted organ. Even though the transplant is proper, it is always advised to continue taking immunosuppressant medication.
But when transplanted tissue is rejected by the recipient's immune system and destroys the transplanted tissue is called as graft rejection. Lymphocytes of specific cell-mediated immunity (T-cells) are responsible for graft rejection.

Multiple choice zoology immune system active and passive immunity immunity related disorders and problems diseases and immunity

Patients who have undergone organ transplants are given anti-rejection medications to

  1. Minimize infection

  2. Stimulate B-macrophage cell interaction

  3. Prevent T-lymphocyte proliferation
  4. Adopt the $HLA$ of donor
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation
  • The drugs that lower the immune system' are called immunosuppressants. 
  • These drugs are given to prevent graft rejection by lowering the immune system's ability to reject the transplanted organ. 
  • If immunity is not lowered the T lymphocytes which are the components of cell-mediated immunity destroy the transplanted tissue causing graft rejection. Thus the correct answer is option C.
Multiple choice zoology immune system active and passive immunity immunity related disorders and problems diseases and immunity

Which of the following is correct for immuno-modulators?

  1. They always suppress immune system

  2. They never suppress immune system

  3. They always stimulate immune system

  4. Specific immuno-modulators stimulate the immuno response of immune system, whereas some other immuno-modulators inhibit it
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Immuno-modulators are natural or synthetic substances that help to regulate or normalise the immune system. There are two types of immuno-modulators viz, immuno-suppressants, which cause immuno-suppression of the immune system and immuno-stimulants (immuno-stimulators) which stimulate immune system by inducing or increasing activity of any of its component. Thus the correct answer is option D.

Multiple choice zoology immune system active and passive immunity immunity related disorders and problems diseases and immunity

Number of haplotypes present in an individual is 

  1. One

  2. Two

  3. Six

  4. Numerous
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

A haplotype (haploid genotype) is a group of alleles in an organism that are inherited together from a single parent. It is used in the collection of specific alleles (that is, specific DNA sequences) in a cluster of tightly linked genes on a chromosome that are likely to be inherited together. An individual will have two haplotypes, although at a population level there may be numerous haplotypes for any given stretch of chromosomal DNA.

So, the correct answer is 'Two'.

Multiple choice zoology immune system active and passive immunity immunity related disorders and problems diseases and immunity

Haplotypes are identical in

  1. Identical twins

  2. Brothers and sisters

  3. Children and parents

  4. All of the above
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

A haplotype (haploid genotype) is a group of alleles in an organism that are inherited together from a single parent. It is used in the collection of specific alleles (that is, specific DNA sequences) in a cluster of tightly linked genes on a chromosome that are likely to be inherited together. The dizygotic twin pairs share two HLA haplotypes more often than ordinary siblings and thus might be genetically more alike.

So, the correct answer is 'Identical twins'.

Multiple choice zoology immune system active and passive immunity immunity related disorders and problems diseases and immunity

Haplotype is

  1. A single genome

  2. Major histocompatability compklex

  3. Chain of HLA alleles inherited together

  4. All of the above
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

A haplotype (haploid genotype) is a group of alleles in an organism that are inherited together from a single parent. It is used in the collection of specific alleles (that is, specific DNA sequences) in a cluster of tightly linked genes on a chromosome that are likely to be inherited together.

So, the correct answer is 'Chain of HLA alleles inherited together'.

Multiple choice zoology immune system active and passive immunity immunity related disorders and problems diseases and immunity

In tissue typing for organ transplant, which of the following is matched?

  1. HLA proteins

  2. HLA alleles

  3. Human leucocyte antigens

  4. Haplotypes
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

The human leukocyte antigen (HLA) system or complex is a gene complex encoding the major histocompatibility complex (MHC) proteins in humans. These cell-surface proteins are responsible for the regulation of the immune system in humans. Tissue typing is a group of procedures that determine the type of histocompatibility antigens on a person's cells or tissues. This procedure is typically used prior to transplantation of tissues or organs. In tissue typing HLA (human leucocyte antigen) are matched.

So, the correct answer is 'Human leucocyte antigens'.

Multiple choice zoology immune system active and passive immunity immunity related disorders and problems diseases and immunity

Obstacle to large scale transplantation of organ is 

  1. Insufficiency of organ donors

  2. Immunological rejection of foreign bodies

  3. Religious or ethnic considerations

  4. Lack of effective surgical techniques
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Organ transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ. The major problem in organ transplantation is transplant rejection, during which the body has an immune response to the transplanted organ(non-self), possibly leading to transplant failure and the need to immediately remove the organ from the recipient.

So, the correct answer is 'Immunological rejection of foreign bodies'.

Multiple choice zoology immune system active and passive immunity immunity related disorders and problems diseases and immunity

Organ transplant rejection is prevented by

  1. Antibodies

  2. New T-cells

  3. immunostimulatory drugs

  4. Immunosuppressant drugs
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Organ transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ. One of the major problem associated with organ transplantation is the transplantation rejection, during which the body has an immune response to the transplanted organ leading to transplant failure and the need to immediately remove the organ from the recipient. In order to prevent the transplant rejection, the immunosuppressant drugs are used which suppresses the immune system responses.

So, the correct answer is 'Immunosuppressant drugs'.