Biology ยท General Awareness
Viral Diseases and Immunity
776 Questions
Viral diseases and immunity cover the structure, transmission, and diagnosis of viruses like HIV. Questions focus on disease pathways, immune responses, and prevention. Strong knowledge here provides an edge in biology scoring.
HIV and AIDS structureVirus transmission methodsImmune system deficiencyPathogen risk groupsMedical diagnosis methods
Viral Diseases and Immunity Questions
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Whitish coating in the throat, tongue or vagina
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Appearance of purple spots in the anus, mouth, nasal passages or on the skin
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Both
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Neither
C
Correct answer
Explanation
Both symptoms described are common manifestations of HIV/AIDS. The whitish coating (thrush) is caused by Candida fungal infection, and purple spots (Kaposi's sarcoma) are a type of cancer associated with advanced HIV. These occur because HIV weakens the immune system, making patients susceptible to opportunistic infections. Therefore option C 'Both' is correct.
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When HIV progresses into AIDS
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The stage immediately after HIV infection when the patient falls ill
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The final fatal disease for the AIDS patient
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None of the above
B
Correct answer
Explanation
Acute HIV Syndrome (also called acute retroviral syndrome or seroconversion illness) refers to the flu-like symptoms that occur 2-4 weeks after initial HIV infection, as the virus rapidly replicates and the body develops antibodies. It is NOT when HIV progresses to AIDS (which takes years), nor is it the final fatal stage. This early stage is often mistaken for common viral illnesses like flu or mononucleosis.
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within a few weeks
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within a year
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in 10 or more years
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any of the above
D
Correct answer
Explanation
HIV symptoms are highly variable and can appear at very different times depending on the individual. Some develop Acute HIV Syndrome within weeks of infection (option A), others may show symptoms within a year (option B), while some may remain asymptomatic for 10 or more years (option C). Since all timelines are possible, option D 'any of the above' is correct.
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Adolescent
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Old age people
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Children
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None of these
A
Correct answer
Explanation
Adolescents (ages 15-24) are most susceptible to HIV infection due to biological factors, risky behaviors, peer pressure, and lack of comprehensive awareness. This age group often engages in unprotected sexual activity and experimentation.
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Within a few weeks
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Within a year
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In 10 or more years
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Any of the above
D
Correct answer
Explanation
HIV symptom onset is highly variable and can occur within weeks (acute HIV syndrome), take years (chronic phase), or may never manifest noticeable symptoms until advanced stages. The timeline depends on individual immune response and viral factors.
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CD4+ T cells
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Macrophages
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dendritic cells
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All of the above
D
Correct answer
Explanation
HIV infects CD4+ T cells (primary target), macrophages, and dendritic cells through CD4 receptors and co-receptors (CCR5, CXCR4). This multi-cell tropism explains the virus's ability to evade immune detection and establish reservoirs.
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Whitish coating in the throat, tongue or vagina
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Appearance of purple spots in the anus, mouth, nasal passages or on the skin
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Both
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Neither
C
Correct answer
Explanation
HIV/AIDS symptoms include whitish coating (oral thrush, candidiasis) indicating fungal infection, and purple spots (Kaposi's sarcoma) which is a cancer. Both are opportunistic conditions common in advanced immunosuppression.
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When HIV progresses into AIDS
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The stage immediately after HIV infection when the patient falls ill
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The final fatal disease for the AIDS patient
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None of the above
B
Correct answer
Explanation
Acute HIV Syndrome (AHS) is the mononucleosis-like illness occurring 2-4 weeks after infection, characterized by fever, rash, and lymphadenopathy. It represents the initial immune response before the chronic phase.
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Blood test
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Urine test
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Westren-bolt test
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No test required (we can say by looking @ the person)
C
Correct answer
Explanation
HIV infection is confirmed through ELISA screening tests, followed by confirmatory Western blot (misspelled as Westren-bolt). The test detects HIV antibodies in blood, with urine tests also available but less common.
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Leukemia
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Breast cancer
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Cervical cancer
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Thyroid cancer
C
Correct answer
Explanation
HIV infection significantly increases the risk of Kaposi's sarcoma, a cancer caused by HHV-8, and certain lymphomas. Among the options listed, cervical cancer has the strongest documented link to HIV - women with HIV have higher rates of cervical dysplasia and cancer due to reduced ability to fight HPV, which causes cervical cancer. The other cancers (leukemia, breast, thyroid) are not specifically HIV-associated.
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Human Immunity Defect Virus
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Human Immuno Deficiency Virus
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Human Immune Deficiency Virus
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None of these
B
Correct answer
Explanation
HIV stands for Human Immunodeficiency Virus. It attacks the body's immune system, specifically CD4 cells (T cells), making it harder to fight infections. Option A has 'Immunity' instead of 'Immuno' and 'Defect' instead of 'Deficiency'. Option C has 'Immune' instead of 'Immuno'.
A
Correct answer
Explanation
HIV can be transmitted through blood, including contaminated needles and equipment used for body piercing or tattooing. If instruments are not properly sterilized between clients and are contaminated with HIV-positive blood, the virus can be passed to the next person. This is why licensed professionals must use sterile, single-use or properly autoclaved equipment.
B
Correct answer
Explanation
HIV (Human Immunodeficiency Virus) is the virus that causes infection, while AIDS (Acquired Immunodeficiency Syndrome) is the late stage of HIV infection when the immune system is severely damaged. A person can live with HIV for many years without developing AIDS, especially with modern antiretroviral therapy. Not everyone with HIV has AIDS.
A
Correct answer
Explanation
This statement is factually accurate. HIV/AIDS has no complete cure, though antiretroviral therapy can manage it. The primary transmission modes are unprotected sexual intercourse and sharing needles with an HIV-positive person.
A
Correct answer
Explanation
Antiretroviral medicines (ARVs) can significantly reduce the risk of HIV transmission from mother to child during pregnancy, childbirth, and breastfeeding. This is known as Prevention of Mother-to-Child Transmission (PMTCT).