Chemistry ยท Biology
Pharmacology and Therapeutics
1,699 Questions
Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.
Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests
Pharmacology and Therapeutics Questions
How many grams of NaCl are needed to prepare 500 mL of a 0.9% NaCl solution?
B
Correct answer
Explanation
Mass of NaCl = (Concentration % / 100) * Volume of solution = (0.9% / 100) * 500 mL = 4.5 g
What is the volume of a 10% dextrose solution needed to deliver 50 g of dextrose?
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250 mL
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500 mL
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750 mL
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1000 mL
B
Correct answer
Explanation
Volume of solution = (Mass of solute / Concentration %) * 100 = (50 g / 10%) * 100 = 500 mL
Which of the following is a solid dosage form?
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Tablet
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Capsule
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Suspension
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Solution
A
Correct answer
Explanation
Tablets are solid dosage forms that are typically swallowed whole.
Which of the following is a controlled-release dosage form?
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Tablet
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Capsule
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Sustained-release tablet
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Solution
C
Correct answer
Explanation
Sustained-release tablets are controlled-release dosage forms that release the drug slowly over a period of time.
Which of these is a common ingredient in energy drinks that can have stimulant effects?
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Taurine
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Guarana
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Ginseng
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All of the above
D
Correct answer
Explanation
Taurine, guarana, and ginseng are all ingredients commonly found in energy drinks that can have stimulant effects.
Which of the following is NOT a major class of drugs used to treat hypertension?
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ACE inhibitors
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Beta-blockers
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Calcium channel blockers
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Antidepressants
D
Correct answer
Explanation
Antidepressants are not typically used to treat hypertension.
What is the mechanism of action of NSAIDs?
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Inhibition of COX-1 and COX-2 enzymes
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Inhibition of phosphodiesterase enzymes
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Activation of alpha-adrenergic receptors
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Blockade of sodium channels
A
Correct answer
Explanation
NSAIDs inhibit the COX-1 and COX-2 enzymes, which are responsible for the production of prostaglandins.
Which of the following drugs is primarily metabolized by the liver?
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Warfarin
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Digoxin
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Insulin
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Epinephrine
A
Correct answer
Explanation
Warfarin is primarily metabolized by the liver.
What is the term for the time it takes for a drug to reach its peak concentration in the blood?
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Half-life
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Onset of action
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Time to maximum concentration
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Duration of action
C
Correct answer
Explanation
The time it takes for a drug to reach its peak concentration in the blood is called the time to maximum concentration.
What is the mechanism of action of statins?
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Inhibition of HMG-CoA reductase
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Inhibition of phosphodiesterase enzymes
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Activation of alpha-adrenergic receptors
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Blockade of sodium channels
A
Correct answer
Explanation
Statins inhibit the HMG-CoA reductase enzyme, which is involved in the production of cholesterol.
Which of the following drugs is a commonly used antihistamine?
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Diphenhydramine
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Acetaminophen
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Omeprazole
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Salmeterol
A
Correct answer
Explanation
Diphenhydramine is a commonly used antihistamine.
What is the term for the process by which a drug is eliminated from the body?
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Absorption
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Distribution
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Metabolism
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Excretion
D
Correct answer
Explanation
The process by which a drug is eliminated from the body is called excretion.
What is the mechanism of action of ACE inhibitors?
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Inhibition of COX-1 and COX-2 enzymes
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Inhibition of phosphodiesterase enzymes
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Inhibition of angiotensin-converting enzyme
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Blockade of sodium channels
C
Correct answer
Explanation
ACE inhibitors inhibit the angiotensin-converting enzyme, which is involved in the production of angiotensin II.
Which of the following drugs is a commonly used anticonvulsant?
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Phenytoin
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Metformin
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Ibuprofen
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Salmeterol
A
Correct answer
Explanation
Phenytoin is a commonly used anticonvulsant.
What is the term for the lowest dose of a drug that produces a therapeutic effect?
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Minimum effective dose
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Maximum tolerated dose
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Therapeutic index
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Median effective dose
A
Correct answer
Explanation
The lowest dose of a drug that produces a therapeutic effect is called the minimum effective dose.