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Pharmacology and Therapeutics
1,699 Questions
Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.
Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests
Pharmacology and Therapeutics Questions
Which of the following is a digitalis glycoside commonly used to treat heart failure and atrial fibrillation?
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Digoxin
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Metoprolol
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Diltiazem
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Warfarin
A
Correct answer
Explanation
Digoxin is a digitalis glycoside that is commonly used to treat heart failure and atrial fibrillation. It works by inhibiting the sodium-potassium pump in the heart, leading to an increase in intracellular calcium and a stronger contraction of the heart muscle.
Which of the following is an anticoagulant commonly used to prevent and treat blood clots?
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Warfarin
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Heparin
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Aspirin
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Clopidogrel
A
Correct answer
Explanation
Warfarin is an anticoagulant that is commonly used to prevent and treat blood clots. It works by inhibiting the synthesis of vitamin K-dependent clotting factors, leading to a decrease in the blood's ability to clot.
Which of the following is an antiplatelet drug commonly used to prevent and treat blood clots?
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Aspirin
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Heparin
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Warfarin
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Clopidogrel
A
Correct answer
Explanation
Aspirin is an antiplatelet drug that is commonly used to prevent and treat blood clots. It works by inhibiting the aggregation of platelets, which are small blood cells that play a role in blood clotting.
Which of the following is a lipid-lowering drug commonly used to treat hyperlipidemia?
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Atorvastatin
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Metformin
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Amiodarone
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Lisinopril
A
Correct answer
Explanation
Atorvastatin is a lipid-lowering drug that is commonly used to treat hyperlipidemia. It works by inhibiting the enzyme HMG-CoA reductase, which is involved in the synthesis of cholesterol in the liver. This leads to a decrease in the levels of LDL cholesterol and triglycerides in the blood.
Which of the following is a biguanide commonly used to treat type 2 diabetes?
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Metformin
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Insulin
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Glipizide
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Pioglitazone
A
Correct answer
Explanation
Metformin is a biguanide that is commonly used to treat type 2 diabetes. It works by decreasing the production of glucose in the liver and improving the sensitivity of cells to insulin, leading to a decrease in blood glucose levels.
Which of the following is a sulfonylurea commonly used to treat type 2 diabetes?
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Glipizide
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Metformin
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Insulin
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Pioglitazone
A
Correct answer
Explanation
Glipizide is a sulfonylurea that is commonly used to treat type 2 diabetes. It works by stimulating the release of insulin from the pancreas, leading to a decrease in blood glucose levels.
Which of the following is a thiazolidinedione commonly used to treat type 2 diabetes?
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Pioglitazone
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Metformin
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Insulin
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Glipizide
A
Correct answer
Explanation
Pioglitazone is a thiazolidinedione that is commonly used to treat type 2 diabetes. It works by improving the sensitivity of cells to insulin, leading to a decrease in blood glucose levels.
Which of the following is an incretin mimetic commonly used to treat type 2 diabetes?
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Exenatide
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Metformin
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Insulin
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Glipizide
A
Correct answer
Explanation
Exenatide is an incretin mimetic that is commonly used to treat type 2 diabetes. It works by mimicking the effects of incretins, which are hormones that are released from the gut after a meal and stimulate the release of insulin from the pancreas. This leads to a decrease in blood glucose levels.
Which of the following is a sodium-glucose cotransporter 2 (SGLT2) inhibitor commonly used to treat type 2 diabetes?
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Canagliflozin
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Metformin
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Insulin
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Glipizide
A
Correct answer
Explanation
Canagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that is commonly used to treat type 2 diabetes. It works by inhibiting the reabsorption of glucose in the kidneys, leading to an increase in the excretion of glucose in the urine and a decrease in blood glucose levels.
Which of the following is a glucagon-like peptide-1 (GLP-1) receptor agonist commonly used to treat type 2 diabetes?
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Liraglutide
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Metformin
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Insulin
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Glipizide
A
Correct answer
Explanation
Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that is commonly used to treat type 2 diabetes. It works by mimicking the effects of GLP-1, which is a hormone that is released from the gut after a meal and stimulates the release of insulin from the pancreas and inhibits the release of glucagon from the pancreas. This leads to a decrease in blood glucose levels.
Which technology is commonly used for the analysis of drug metabolism and pharmacokinetics?
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Mass spectrometry
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Chromatography
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Electrophoresis
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Spectrophotometry
A
Correct answer
Explanation
Mass spectrometry is widely used for the analysis of drug metabolism and pharmacokinetics, allowing researchers to study the absorption, distribution, metabolism, and excretion of drugs in the body.
What is the treatment for a poultry allergy or intolerance?
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Antihistamines
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Decongestants
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Steroids
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All of the above
D
Correct answer
Explanation
All of the above medications can be used to treat a poultry allergy or intolerance.
Which of the following is NOT a treatment for a poultry allergy?
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Antihistamines
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Decongestants
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Steroids
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Immunotherapy
D
Correct answer
Explanation
Immunotherapy is not a treatment for a poultry allergy.
Which of the following medications is commonly used to treat mild to moderate Crohn's Disease?
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5-Aminosalicylates (5-ASAs)
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Corticosteroids
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Immunomodulators
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Biologics
A
Correct answer
Explanation
5-Aminosalicylates (5-ASAs) are commonly used to treat mild to moderate Crohn's Disease due to their ability to reduce inflammation in the digestive tract.
What is the concentration of a solution that contains 50 mg of solute in 100 mL of solution?
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0.5 mg/mL
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5 mg/mL
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50 mg/mL
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500 mg/mL
B
Correct answer
Explanation
Concentration = (Mass of solute / Volume of solution) = (50 mg / 100 mL) = 5 mg/mL