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Pharmacology and Therapeutics
1,643 Questions
Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.
Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests
Pharmacology and Therapeutics Questions
Which of the following is an incretin mimetic commonly used to treat type 2 diabetes?
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Exenatide
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Metformin
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Insulin
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Glipizide
A
Correct answer
Explanation
Exenatide is an incretin mimetic that is commonly used to treat type 2 diabetes. It works by mimicking the effects of incretins, which are hormones that are released from the gut after a meal and stimulate the release of insulin from the pancreas. This leads to a decrease in blood glucose levels.
Which of the following is a sodium-glucose cotransporter 2 (SGLT2) inhibitor commonly used to treat type 2 diabetes?
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Canagliflozin
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Metformin
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Insulin
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Glipizide
A
Correct answer
Explanation
Canagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that is commonly used to treat type 2 diabetes. It works by inhibiting the reabsorption of glucose in the kidneys, leading to an increase in the excretion of glucose in the urine and a decrease in blood glucose levels.
Which of the following is a glucagon-like peptide-1 (GLP-1) receptor agonist commonly used to treat type 2 diabetes?
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Liraglutide
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Metformin
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Insulin
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Glipizide
A
Correct answer
Explanation
Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that is commonly used to treat type 2 diabetes. It works by mimicking the effects of GLP-1, which is a hormone that is released from the gut after a meal and stimulates the release of insulin from the pancreas and inhibits the release of glucagon from the pancreas. This leads to a decrease in blood glucose levels.
Which technology is commonly used for the analysis of drug metabolism and pharmacokinetics?
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Mass spectrometry
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Chromatography
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Electrophoresis
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Spectrophotometry
A
Correct answer
Explanation
Mass spectrometry is widely used for the analysis of drug metabolism and pharmacokinetics, allowing researchers to study the absorption, distribution, metabolism, and excretion of drugs in the body.
What is the treatment for a poultry allergy or intolerance?
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Antihistamines
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Decongestants
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Steroids
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All of the above
D
Correct answer
Explanation
All of the above medications can be used to treat a poultry allergy or intolerance.
Which of the following is NOT a treatment for a poultry allergy?
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Antihistamines
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Decongestants
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Steroids
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Immunotherapy
D
Correct answer
Explanation
Immunotherapy is not a treatment for a poultry allergy.
Which of the following medications is commonly used to treat mild to moderate Crohn's Disease?
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5-Aminosalicylates (5-ASAs)
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Corticosteroids
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Immunomodulators
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Biologics
A
Correct answer
Explanation
5-Aminosalicylates (5-ASAs) are commonly used to treat mild to moderate Crohn's Disease due to their ability to reduce inflammation in the digestive tract.
Which of the following is NOT a recommended ingredient for an intra-workout drink?
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Artificial sweeteners
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Caffeine
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BCAAs
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Creatine
A
Correct answer
Explanation
Artificial sweeteners are not recommended for intra-workout drinks as they can cause gastrointestinal distress and may interfere with the absorption of other nutrients.
Which of the following is a solid dosage form?
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Tablet
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Capsule
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Suspension
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Solution
A
Correct answer
Explanation
Tablets are solid dosage forms that are typically swallowed whole.
Which of the following is a controlled-release dosage form?
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Tablet
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Capsule
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Sustained-release tablet
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Solution
C
Correct answer
Explanation
Sustained-release tablets are controlled-release dosage forms that release the drug slowly over a period of time.
Which of these is a common ingredient in energy drinks that can have stimulant effects?
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Taurine
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Guarana
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Ginseng
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All of the above
D
Correct answer
Explanation
Taurine, guarana, and ginseng are all ingredients commonly found in energy drinks that can have stimulant effects.
Which of the following is NOT a major class of drugs used to treat hypertension?
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ACE inhibitors
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Beta-blockers
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Calcium channel blockers
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Antidepressants
D
Correct answer
Explanation
Antidepressants are not typically used to treat hypertension.
What is the mechanism of action of NSAIDs?
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Inhibition of COX-1 and COX-2 enzymes
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Inhibition of phosphodiesterase enzymes
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Activation of alpha-adrenergic receptors
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Blockade of sodium channels
A
Correct answer
Explanation
NSAIDs inhibit the COX-1 and COX-2 enzymes, which are responsible for the production of prostaglandins.
Which of the following drugs is primarily metabolized by the liver?
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Warfarin
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Digoxin
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Insulin
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Epinephrine
A
Correct answer
Explanation
Warfarin is primarily metabolized by the liver.
What is the term for the time it takes for a drug to reach its peak concentration in the blood?
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Half-life
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Onset of action
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Time to maximum concentration
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Duration of action
C
Correct answer
Explanation
The time it takes for a drug to reach its peak concentration in the blood is called the time to maximum concentration.