Chemistry · Biology

Pharmacology and Therapeutics

1,643 Questions

Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.

Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests

Pharmacology and Therapeutics Questions

Multiple choice

Which of the following drugs is contraindicated in cataract?

  1. Aseclofenac

  2. Sedatives

  3. Laxatives

  4. Corticosteroids

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Corticosteroids can accelerate cataract formation and are contraindicated in patients with cataracts. Aceclofenac (typo: Aseclofenac) is an NSAID used for pain. Sedatives and laxatives don't directly affect cataract formation or progression.

Multiple choice

Ciclosporin is an immuno-suppressant substance widely used in organ transplantation to prevent rejection. It is secreted by

  1. Tolypocladium niveum

  2. Schizosaccharomyces pombe

  3. Saccharomyces cerevisiae

  4. Penicillium camemberti

  5. Aspergillus oryzae
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

The medical importance of Tolypocladium niveum as an immunosuppressor can hardly be exaggerated. It excretes Ciclosporin, which, as well as being given during Organ transplantation to prevent rejection, is also prescribed for auto-immune diseases such as multiple sclerosis.

Multiple choice

Which of the following statements is correct?

  1. Tartar emetic is used as a medicine (emetic) for the treatment of vomiting and poisoning.

  2. Tartar emetic is used for the preparation of Fehling's solution.

  3. Tartar emetic is used for the fermentation of dilute solution of sugar.

  4. Tartar emetic is used for making blueprints.

  5. Tartar emetic is used for making baking powder.
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

This option is correct.

Multiple choice

The chemical compound used in narco test is

  1. sodium hypochlorite

  2. LSD

  3. sodium pentothal

  4. None of these
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Sodium pentothal (thiopental sodium) is a barbiturate drug used as a 'truth serum' in forensic interrogations due to its inhibitory effect on the central nervous system. It lowers inhibitions and can make subjects more forthcoming during questioning. Sodium hypochlorite is bleach, and LSD is a hallucinogen.

Multiple choice

Match the columns:

 
Column I Column II
P. Niclosamide 1. Inhibits absorption of nutrients
Q. Praziquantel 2. Neuromuscular block
R. Pyantel pamoate 3. Alters permeability of plasma membranes
S. Mebendazole 4. Prevents ATP generation in mitochondria

  1. P - 1; Q - 2; R - 3; S - 4

  2. P - 2; Q - 3; R - 4; S - 1

  3. P - 2; Q - 4; R - 3; S - 1

  4. P - 3; Q - 4; R - 2; S - 1

  5. P - 4; Q - 3; R - 2; S - 1
Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

Niclosamide is an anti-helmintic drug used in the treatment of tapeworm infection.

Multiple choice

Which of the following US companies made the drug ZMapp available to treat Ebola?

  1. Pfizer

  2. Mapp Biopharmaceutical

  3. Novartis

  4. Astra Zeneca

  5. GlaxoSmithKline
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Mapp Biopharmaceutical, a US-based company, developed ZMapp as a treatment for Ebola virus disease. The drug gained attention during the 2014-2016 Ebola outbreak in West Africa. Other companies listed (Pfizer, Novartis, Astra Zeneca, GlaxoSmithKline) are major pharmaceutical companies but not associated with ZMapp.

Multiple choice

Which of the following is a pair of synthetic estrogens?

  1. Estrone and Estriol

  2. Diethylstilbestrol and Fosfestrol

  3. Estriol and Fosfestrol

  4. Chlorotrianisene and Estrone

  5. Estrone and Fosfestrol
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Correct answer. Diethylstilbestrol is a synthetic nonsteroidal estrogen that was first synthesised in 1938. Fosfestrol is a synthetic estrogen used as an antineoplastic agent.

Multiple choice

The substance used as anaesthetic is

  1. nitrous oxide

  2. iodoform

  3. aspirin

  4. amatol
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Nitrous oxide (N2O, laughing gas) has been used as an anesthetic since the 18th century. It produces analgesic and anesthetic effects when inhaled, reducing pain sensation and inducing unconsciousness in higher concentrations. It remains widely used in dentistry and minor surgical procedures due to its rapid onset and quick recovery.