Biology

Molecular Biology and Genetics

985 Questions

Molecular biology and genetics explore the structure and function of DNA, RNA, genetic mutations, and heredity. Understanding these building blocks of life is essential for most biology examinations. Review these practice questions to test your molecular genetics knowledge.

DNA structure and basesGenetic mutationsNucleic acids compositionDNA sequencing and replication

Molecular Biology and Genetics Questions

Multiple choice
  1. hydrogen bonds between base

  2. phosphodiester bonds

  3. disulphide bonds

  4. covalnet bonds

  5. -

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Correct Answer: hydrogen bonds between base

Multiple choice
  1. DNA and histone

  2. DNA and no histone

  3. no DNA and histone

  4. no DNA and no histone

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Prokaryotes have circular DNA not coiled into chromosomes. It has no histone unlike eukaryotes.

Multiple choice
  1. C-DNA

  2. B-DNA

  3. D-DNA

  4. Z-DNA

  5. -

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

In B-DNA, the most common double helical structure, the double helix is right-handed with about 10–10.5 base pairs per turn. In B-DNA, the major groove is wider than the minor groove. Given the difference in widths of the major groove and minor groove, many proteins which bind to B-DNA do so through the wider major groove.

Multiple choice
  1. Albinism

  2. Porphyria

  3. Wilson's disease

  4. Phenylketonuria

  5. -

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Phenylketonuria (PKU) is an inborn error of metabolism involving impaired metabolism of phenylalanine.

Multiple choice
  1. single nucleotide

  2. two nucleotides

  3. three nucleotides

  4. four nucleotides

  5. -

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

A codon is a sequence of three DNA or RNA nucleotides that corresponds with a specific amino acid or stop signal during protein synthesis. DNA and RNA molecules are written in a language of four nucleotides.

Multiple choice
  1. TAA; UTT; methionine

  2. TAA; AUU; no amino acid (= stop codon)

  3. UAA; AUU; no amino acid (= stop codon)

  4. CGG; GCC; alanine

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

The complementary base-pairing rules of DNA-to-RNA and RNA-to -RNA give the codon and anticodon. Recall also that there is no thymine in RNA; uracil and adenine are complementary bases for RNA.

Multiple choice
  1. frame shift mutations

  2. base pair substitutions

  3. Both (1) and (2)

  4. None of these

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Gene mutation or point mutation is the result of a change in the nucleotide sequence of the DNA molecule in a particular region of the chromosome. Gene mutation occurs in the form of duplication, insertion, deletion, inversion or substitution of bases. The addition or deletion of a base may change the reading frame of nucleotide sequence. This is called frame-shift mutation.

Multiple choice
  1. The sugar-phosphate chain on the outside and the bases on the inside are held together by weak hydrogen bonds.

  2. The sugar-phosphate chain on the inside and the bases on the outside are held together by weak hydrogen bonds.

  3. The sugar-phosphate chain on the outside and the bases on the inside are held together by strong hydrogen bonds.

  4. The sugar-phosphate chain on the inside and the bases on the outside are held together by strong hydrogen bonds.

  5. None of these

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Yes, it is correct.