Biology
Molecular Biology and Genetics
985 Questions
Molecular biology and genetics explore the structure and function of DNA, RNA, genetic mutations, and heredity. Understanding these building blocks of life is essential for most biology examinations. Review these practice questions to test your molecular genetics knowledge.
DNA structure and basesGenetic mutationsNucleic acids compositionDNA sequencing and replication
Molecular Biology and Genetics Questions
-
E.coli
-
Sacchromyces cereviceae
-
Coaenorhabditis elegans
-
Drosophila melanogaster
-
None of these
A
Correct answer
Explanation
It has 4.7 million base pairs.
-
hydrogen bonds between base
-
phosphodiester bonds
-
disulphide bonds
-
covalnet bonds
-
-
A
Correct answer
Explanation
Correct Answer: hydrogen bonds between base
-
TCGATTTCG
-
ACGAUUCG
-
AGCTAAGC
-
CAUTAUCG
-
-
A
Correct answer
Explanation
Correct Answer: TCGATTTCG
-
Base pairs are formed by hydrogen bonds.
-
It contains nitrogenous base pairs.
-
It is a single helix structure.
-
Strands are made of sugar-phosphate backbone.
C
Correct answer
Explanation
It is a double helix structure.
-
DNA and histone
-
DNA and no histone
-
no DNA and histone
-
no DNA and no histone
B
Correct answer
Explanation
Prokaryotes have circular DNA not coiled into chromosomes. It has no histone unlike eukaryotes.
-
C-DNA
-
B-DNA
-
D-DNA
-
Z-DNA
-
-
B
Correct answer
Explanation
In B-DNA, the most common double helical structure, the double helix is right-handed with about 10–10.5 base pairs per turn. In B-DNA, the major groove is wider than the minor groove. Given the difference in widths of the major groove and minor groove, many proteins which bind to B-DNA do so through the wider major groove.
-
frame shift mutations
-
base pair substitutions
-
Both 1 and 2
-
None of the above
-
-
C
Correct answer
Explanation
Correct Answer: Both 1 and 2
-
Albinism
-
Porphyria
-
Wilson's disease
-
Phenylketonuria
-
-
D
Correct answer
Explanation
Phenylketonuria (PKU) is an inborn error of metabolism involving impaired metabolism of phenylalanine.
-
single nucleotide
-
two nucleotides
-
three nucleotides
-
four nucleotides
-
-
C
Correct answer
Explanation
A codon is a sequence of three DNA or RNA nucleotides that corresponds with a specific amino acid or stop signal during protein synthesis. DNA and RNA molecules are written in a language of four nucleotides.
A
Correct answer
Explanation
The correct option is (1).
-
TAA; UTT; methionine
-
TAA; AUU; no amino acid (= stop codon)
-
UAA; AUU; no amino acid (= stop codon)
-
CGG; GCC; alanine
C
Correct answer
Explanation
The complementary base-pairing rules of DNA-to-RNA and RNA-to -RNA give the codon and anticodon. Recall also that there is no thymine in RNA; uracil and adenine are complementary bases for RNA.
-
By super-coiling in nucleosomes
-
By DNAse digestion
-
By elimination of repetitive DNA
-
By deletion of non-essential genes
A
Correct answer
Explanation
The nucleosome model explains the packaging of histone proteins and DNA in the chromatin material, which forms the chromosome.
B
Correct answer
Explanation
On each strand, 50,000 spirals would occur. One spiral has 10 nucleotides. Therefore, 500000/10 spirals = 50000 spirals.
-
frame shift mutations
-
base pair substitutions
-
Both (1) and (2)
-
None of these
A
Correct answer
Explanation
Gene mutation or point mutation is the result of a change in the nucleotide sequence of the DNA molecule in a particular region of the chromosome. Gene mutation occurs in the form of duplication, insertion, deletion, inversion or substitution of bases. The addition or deletion of a base may change the reading frame of nucleotide sequence. This is called frame-shift mutation.
-
The sugar-phosphate chain on the outside and the bases on the inside are held together by weak hydrogen bonds.
-
The sugar-phosphate chain on the inside and the bases on the outside are held together by weak hydrogen bonds.
-
The sugar-phosphate chain on the outside and the bases on the inside are held together by strong hydrogen bonds.
-
The sugar-phosphate chain on the inside and the bases on the outside are held together by strong hydrogen bonds.
-
None of these