Biology · Science General

Disease Causative Agents

2,531 Questions

Disease causative agents questions test your understanding of viral, bacterial, and fungal infections, along with their transmission methods. These are common topics in general science sections of SSC and railways exams. Practice these questions to accurately identify disease pathogens and symptoms.

Viral diseasesFoodborne illnessesDisease transmission methodsExtrinsic disease factorsCommon pathogens

Disease Causative Agents Questions

Multiple choice

The causal organism of gonorrhea is a _____________.

  1. bacteria

  2. fungi

  3. virus

  4. worm
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Gonorrhea is a sexually transmitted infection caused by Neisseria gonorrhoeae, which is a bacterium. It specifically infects the mucous membranes of the reproductive and urinary tracts. Fungi, viruses, and worms cause different types of infections.

Multiple choice

Raynaud's phenomenon is observed in which of the following autoimmune diseases?

  1. Wegener's granulomatosis

  2. Systemic necrotizing vasculitides

  3. Sarcoidosis

  4. Diffuse scleroderma
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Diffuse scleroderma can cause musculoskeletal, pulmonary, gastrointestinal, renal and other complications. Raynaud's phenomenon is observed in diffuse scleroderma. Raynaud's phenomenon causes excessive reduced blood flow in response to cold or emotional stress, discolouration of the fingers, toes and occasionally other areas.

Multiple choice

Penetration of epithelial layers follows adherence in most infections. In which of the following ways does Vibrio cholerae cause damage to the epithelial cells of the body?

  1. By passive penetration

  2. By active penetration

  3. It damages without penetration

  4. Both by active and passive penetration, as per the situation
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Vibrio cholerae does not penetrate epithelial surface. It causes damage without penetration in the body. It multiplies on the epithelial surface and produces a toxin that causes loss of fluid from the epithelial cells and kills cells.

Multiple choice

Match the columns:

 
Side A Side B
1. Tetanus a. Acetylcholine
2. Botulism b. Elongation factor
3. Cholera c. Inhibitory factor
4. Diphtheria d. Adenylate cyclase
  1. 1. Tetanus c. Inhibitory factor
    2. Botulism d. Adenylate cyclase
    3. Cholera b. Elongation factor
    4. Diphtheria a. Acetylcholine
  2. 1. Tetanus a. Acetylcholine
    2. Botulism c. Inhibitory factor
    3. Cholera d. Adenylate cyclase
    4. Diphtheria b. Elongation factor
  3. 1. Tetanus c. Inhibitory factor
    2. Botulism a. Acetylcholine
    3. Cholera d. Adenylate cyclase
    4. Diphtheria b. Elongation factor
  4. 1. Tetanus d. Adenylate cyclase
    2. Botulism b. Elongation factor
    3. Cholera a. Acetylcholine
    4. Diphtheria c. Inhibitory factor
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

This is the correct match. Tetanus toxin acts on the central nervous system to prevent the release of inhibitory factor. In botulism, the toxin binds to the axon near the neuromuscular junction and prevents the secretion of acetylcholine. Cholera toxin hampers the activity of the enzyme adenylate cyclase in the cell. Diphtheria toxin inactivates elongation factor 2.

Multiple choice

Which of the following matches is incorrect?

  1. Gull’s disease : Myxoedema

  2. Addison-Biermer’s disease : Pernicious anemia

  3. Hodgkin’s disease : Lymphoma

  4. Riggs' disease : Pyorrhoea

  5. Koch’s disease : Leprosy
Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

Koch’s disease is also known as Tuberculosis (TB) is a potentially fatal contagious disease that can affect almost any part of the body but is mainly an infection of the lungs. It is caused by a bacterial microorganism, the tubercle bacillus or Mycobacterium tuberculosis whereas Leprosy, also known as Hansen's disease (HD), is a chronic infection caused by the bacteria Mycobacterium leprae and Mycobacterium lepromatosis.

Multiple choice

Directions: Select the correct alternative from the given choices.

Which disease is caused by corona virus?

  1. Bronchitis

  2. Diphtheria

  3. SARS

  4. Whooping cough
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

SARS (Severe Acute Respiratory Syndrome) is caused by the SARS-CoV-1, a coronavirus. It emerged in 2002-2003 and caused a global outbreak. The other options are caused by different pathogens: Bronchitis is usually viral or bacterial, Diphtheria is bacterial, and Whooping cough is caused by Bordetella pertussis bacteria.

Multiple choice

Which of the following statements is true regarding enteropathogenic E. coli?

  1. It produces a heat labile toxin.

  2. It invades epithelial cells of the large intestine.

  3. It colonises jejunum and upper ileum of the small intestine.

  4. It is an opportunistic infectant, otherwise it resides on human body as normal flora.
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Enteropathogenic E. coli colonises jejunum and upper ileum of the small intestine. It causes a moderate to severe gastroenteritis in humans and animals.