Multiple choice RNA primers are necessary in DNA synthesis because DNA polymerase can only add to an existing strand of nucleotides DNA polymerase can only add to an existing DNA strand DNA primase is the first enzyme in the replication complex. All of the above Reveal answer Fill a bubble to check yourself A Correct answer Explanation DNA polymerase cannot initiate the building of a nucleotide strand; it can only add to an existing strand. Thus, RNA primers are necessary to begin DNA synthesis.