Multiple choice

Post-streptococcal glomerulonephritis may develop a week or two after recovery from a streptococcal throat infection. Which of the following statements is true about acute post-streptococcal glomerulonephritis?

  1. It only occurs following upper respiratory tract infection.

  2. It typically follows within 5 days of streptococcal infection.

  3. The anti-DNAse B titre is a better indicator of streptococcal skin sepsis than the ASO titre.

  4. It is consistently associated with a normal C3 level in the early phase.

  5. Only 10% children recover completely after the clinical course.
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Cholesterol and lipids in skin modify the antigenicity of streptolysin O and suppress the ASO antibody response, but not the anti-DNAse B antibody titre.

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