Multiple choice

The pyrogenic streptococcal exotoxins SPE, A, B, and C ____________.

  1. are M proteins

  2. cause post-streptococcal autoimmune disease

  3. produce high titers of anti-streptolysin O

  4. have hyaluronidase activity

  5. are superantigens

Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

The superantigens combine with the framework regions of certain TCR V beta families irrespective of their complementarity determining regions.