Multiple choice

A dominantly inherited trait affects a 12 year old boy and his grandmother, but not the parents. This best illustrates which of the following principles?

  1. Variable expressivity

  2. New mutation

  3. Somatic mosaicism

  4. Nonpenetrance

  5. Germline mosaicism

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Non-penetrance means that a person has inherited the genetic change, but that it does not manifest the associated phenotype.