Multiple choice

A dominantly inherited trait affects a newborn baby of Verma family and his grandmother, but neither parent. Which of the following principles does it illustrate?

  1. Variable expressivity

  2. Somatic mosaicism

  3. Germline mosaicism

  4. Non-penetrance

  5. Somatic mutations

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Non-penetrance means that a person has inherited the genetic change, but that it does not manifest the associated phenotype. A skipped generation for a dominant trait is an example of non-penetrance.