Multiple choice

Positive selection was first demonstrated in classic experiments using mice. In thymus, it is mediated by

  1. macrophages

  2. thymic epithelial cells

  3. dendritic cells

  4. B-cells

  5. T-cells
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Cortical epithelial cells may be relatively inefficient antigen processors and only deliver a weak signal which induces proliferation rather than deletion of immature thymocytes.

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