Multiple choice

Which of the following statements is TRUE regarding DNA vaccines?

  1. They are relatively poor at stimulating cytotoxic T lymphocyte responses in mice.

  2. Must be administered on gold particles if they are to be effective.

  3. They are only effective if followed by a protein boost.

  4. May have distinct advantages when preparing subunit vaccines against viruses which frequently alter their antigens.

  5. Require cold storage in tropical countries.
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Subunit vaccines require lengthy protein synthesis and purification procedures, DNA vaccines circumvent this and DNA from the current variants of, for example, influenza virus, could be rapidly isolated and replicated for use in a DNA vaccine.

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