Multiple choice

Antiemetic with most affinity for 5Ht3 is

  1. ondansetron

  2. granisetron

  3. dolasetron

  4. pavalosetron
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Palonosetron has the highest affinity and longest duration among 5-HT3 antagonists due to its unique receptor binding properties. Ondansetron, granisetron, and dolasetron are all 5-HT3 antagonists but palonosetron's binding affinity is superior. This translates to extended antiemetic effect.

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