Multiple choice general knowledge

The inhibitors of 5-HT3 serotonin receptors (setrons) are usually used as:

  1. antidepressants

  2. CNS stimulants

  3. antiemetic agents

  4. anxiolytic agents

  5. antiepileptic drugs
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C Correct answer
Explanation

5-HT3 receptor antagonists (setrons like ondansetron, granisetron) work by blocking serotonin receptors in the gut and CNS's chemoreceptor trigger zone. Their primary clinical use is as antiemetic agents for preventing and treating nausea and vomiting, especially chemotherapy-induced and post-operative nausea. They are not antidepressants, CNS stimulants, anxiolytics, or antiepileptics.

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